AIMC Topic: Machine Learning

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Assessing the effect of perfluoroalkyl and polyfluoroalkyl substances on cardiovascular-kidney-metabolic syndrome: Insights from an interpretable machine learning model.

The Science of the total environment
Cardiovascular-kidney-metabolic syndrome (CKM) and its association with exposure to emerging pollutants, particularly perfluoroalkyl and polyfluoroalkyl substances (PFAS), present significant challenges for environmental public health and risk predic...

Genetic features for drug responses in cancer - Investigating an ensemble-feature-selection approach.

Computers in biology and medicine
Predicting drug responses using genetic and transcriptomic features is crucial for enhancing personalized medicine. In this study, we implemented an ensemble of machine learning algorithms to analyze the correlation between genetic and transcriptomic...

Optimizing machine learning methods for groundwater quality prediction: Case study in District Bagh, Azad Kashmir, Pakistan.

Ecotoxicology and environmental safety
Groundwater quality monitoring is crucial for protecting the environment and human health. Machine learning (ML) offers substantial potential for enhancing groundwater quality prediction, classification, and identification of pollution indicators. Th...

Multi-modal models using fMRI, urine and serum biomarkers for classification and risk prognosis in diabetic kidney disease.

Diabetes, obesity & metabolism
BACKGROUND: Functional magnetic resonance imaging (fMRI) is a powerful tool for non-invasive evaluation of micro-changes in the kidneys. This study aims to develop classification and prognostic models based on multi-modal data.

De novo design and bioactivity prediction of mitotic kinesin Eg5 inhibitors using MPNN and LSTM-based transfer learning.

Computers in biology and medicine
Breast cancer, the most commonly diagnosed disease worldwide, has been linked to the overexpression of the kinesin Eg5 protein, a spindle motor protein crucial for the assembly and maintenance of the bipolar spindle during mitosis. This makes Eg5 an ...

A new method for internal urinary metabolite exposure and dietary exposure association assessment of 3-MCPD and glycidol and their esters based on machine learning.

Ecotoxicology and environmental safety
3-Monochloropropane-1,2-diol (3-MCPD) and glycidol along with their esters are commonly found in chemical production, wastewater treatment, food processing, and exhibit toxicity. Accurate exposure assessment is essential for evaluating the environmen...

Two-stage ensemble learning framework for automated classification of keratoconus severity.

Computers in biology and medicine
BACKGROUND AND OBJECTIVE: Accurate staging of keratoconus (KC) is crucial for timely intervention and improving patient quality of life. Unlike prior studies that relied on traditional base machine learning (ML) models, this paper proposes a more adv...

CRCpred: An AI-ML tool for colorectal cancer prediction using gut microbiome.

Computers in biology and medicine
Colorectal cancer (CRC) is a leading cause of death worldwide. A plethora of research shows the alteration of the gut microbiome and the association of bacterial taxa with CRC. Gaining insights into the health status through microbiome-based diagnosi...

Machine learning prediction models for stroke-associated pneumonia:Meta-analysis.

Computers in biology and medicine
OBJECTIVE: The heterogeneity of machine learning (ML) models predicting the risk of stroke-associated pneumonia (SAP) is considerable. This study aims to conduct a meta-analysis and comparison of published ML models that predict SAP risk.

Methodology for contamination detection and reduction in fermentation processes using machine learning.

Bioprocess and biosystems engineering
This paper demonstrates an accurate and efficient methodology for fermentation contamination detection and reduction using two machine learning (ML) methods, including one-class support vector machine and autoencoders. We also optimize as many hyperp...