The Ames mutagenicity test is a gold standard assay for the safety assessment of new chemicals. However, many in silico models rely on challenging-to-interpret ensemble strategies and molecular fingerprint data, which neglects gestalt molecular struc...
The N-heptad repeat (NHR) of the HIV-1 gp41 prehairpin intermediate (PHI) is an attractive potential vaccine target with high sequence conservation across diverse strains. However, despite the potency of NHR-targeting peptides and clinical efficacy o...
High-throughput screening and computational models have been effective in predicting chemical interactions with estrogen and androgen receptors, but similar approaches for steroidogenesis remain limited. To address this gap, we developed general ster...
Viruses are transmitted through multiple routes and can cause a wide range of diseases. Antiviral peptides (AVPs) have emerged as a cost-effective and low-side-effect strategy for combating viral infections. However, identifying antiviral peptides ex...
Ecotoxicology and environmental safety
Jul 15, 2025
The link between individual metals and gestational anemia has been established, but the impact of metal mixtures and the mediating role of renal function on gestational anemia remain inconclusive. The concentrations of 20 blood essential trace and no...
Accurate prediction of depressive symptoms in healthy individuals can enable early intervention and reduce both individual and societal costs. This study aimed to develop predictive models for depression in young adults using machine learning (ML) te...
There is a substantial knowledge gap in the narcissism literature: <1 % of the nearly 12,000 articles on narcissism have addressed its neural basis. To help fill this gap, we asked whether the multifacetedness of narcissism could be decoded from spon...
An efficient machine learning model was developed to accurately predict the sintering temperature of ceramsite synthesized from various solid waste materials. Based on experimental data from 236 samples, eight key chemical components were defined as ...
Clinica chimica acta; international journal of clinical chemistry
Jul 15, 2025
Urothelial carcinoma (UC) is a highly malignant disease with significant public health implications. Despite advancements in oncology, early diagnosis and effective prognostic tools remain limited. This study aimed to develop a machine learning model...
Black carbon (BC) is a short-lived pollutant with significant environment and human health impacts. Monitoring BC is important, but its spatial coverage is limited. Therefore, predicting BC concentration is crucial in densely populated regions like t...
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