Chinese Hamster Ovary (CHO) cells are the most widely used cell lines to produce recombinant therapeutic proteins such as monoclonal antibodies (mAbs). However, the optimization of the CHO cell culture process is very complex and influenced by variou...
OBJECTIVE: Development of novel drug solutions has always been an expensive endeavour, hence drug repurposing as an approach has gained popularity in recent years. In this review we intend to examine one of the most unique computational methods for d...
OBJECTIVE: This umbrella review of reviews aims to synthesise current evidence on AI's utilisation in developing education within health sciences disciplines.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Jan 31, 2025
OBJECTIVE: Multi-day assessments accurately identify patients with left-sided breast cancer who are ineligible for irradiation in Deep Inspiration Breath Hold (DIBH) and minimise on-couch treatment time in those who are eligible. The challenge of imp...
BACKGROUND: Alzheimer's disease (AD) and frontotemporal dementia (FTD) are both progressive neurological disorders that affect the elderly. Distinguishing between individuals suffering from these two diseases in the early stages can be quite challeng...
OBJECTIVE: To develop a machine learning (ML) model using clinical data and ultrasound features for gout prediction, and apply SHapley Additive exPlanations (SHAP) for model interpretation.
Journal of chemical information and modeling
Jan 31, 2025
The efficiency of machine learning (ML) models is crucial to minimize inference times and reduce the carbon footprints of models deployed in production environments. Current models employed in retrosynthesis to generate a synthesis route from a targe...
BACKGROUND: Determining spatial relationships between diseases and the exposome is limited by available methodologies. aPEER (algorithm for Projection of Exposome and Epidemiological Relationships) uses machine learning (ML) and network analysis to f...
Nutrient pollution caused by excessive total nitrogen (TN) and total phosphorus (TP) is a significant environmental challenge globally, threatening water quality and ecosystem health. This study investigates the interplay between rainfall, topography...
This paper explores the use of personalized cognitive support through social robots to assist the elderly in maintaining cognitive health and emotional well-being. As aging populations grow, the demand for innovative solutions to address issues like ...
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