AIMC Topic: Macular Degeneration

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A comprehensive review on early detection of drusen patterns in age-related macular degeneration using deep learning models.

Photodiagnosis and photodynamic therapy
Age-related Macular Degeneration (AMD) is a leading cause of visual impairment and blindness that affects the eye from the age of fifty-five and older. It impacts on the retina, the light-sensitive layer of the eye. In early AMD, yellowish deposits c...

Integrative analysis and knowledgebase construction of key candidate genes and pathways in age-related macular degeneration.

Experimental eye research
Age-related macular degeneration is a retinal disease that severely impacts vision in the older population. Its gene-related heterogeneity has not been fully studied, increasing the burden of precise treatment, prevention and prognosis. Genetic varia...

Artificial intelligence in assessing progression of age-related macular degeneration.

Eye (London, England)
The human population is steadily growing with increased life expectancy, impacting the prevalence of age-dependent diseases, including age-related macular degeneration (AMD). Health care systems are confronted with an increasing burden with rising pa...

Anti-VEGF treatment outcome prediction based on optical coherence tomography images in neovascular age-related macular degeneration using a deep neural network.

Scientific reports
Age-related macular degeneration (AMD) is a major cause of blindness in developed countries, and the number of affected patients is increasing worldwide. Intravitreal injections of anti-vascular endothelial growth factor (VEGF) are the standard thera...

Topographic and quantitative correlation of structure and function using deep learning in subclinical biomarkers of intermediate age-related macular degeneration.

Scientific reports
To examine the morphological impact of deep learning (DL)-quantified biomarkers on point-wise sensitivity (PWS) using microperimetry (MP) and optical coherence tomography (OCT) in intermediate AMD (iAMD). Patients with iAMD were examined by OCT (Spec...

Recent advances in the application of artificial intelligence in age-related macular degeneration.

BMJ open ophthalmology
Recent advancements in ophthalmology have been driven by the incorporation of artificial intelligence (AI), especially in diagnosing, monitoring treatment and predicting outcomes for age-related macular degeneration (AMD). AMD is a leading cause of i...

A Novel Management Challenge in Age-Related Macular Degeneration: Artificial Intelligence and Expert Prediction of Geographic Atrophy.

Ophthalmology. Retina
PURPOSE: The progression of geographic atrophy (GA) secondary to age-related macular degeneration is highly variable among individuals. Prediction of the progression is critical to identify patients who will benefit most from the first treatments cur...

Cross-instrument optical coherence tomography-angiography (OCTA)-based prediction of age-related macular degeneration (AMD) disease activity using artificial intelligence.

Scientific reports
This study investigates the efficacy of predicting age-related macular degeneration (AMD) activity through deep neural networks (DNN) using a cross-instrument training dataset composed of Optical coherence tomography-angiography (OCTA) images from tw...

Machine learning model for age-related macular degeneration based on heavy metals: The National Health and Nutrition Examination Survey 2005 to 2008.

Scientific reports
Age-related macular degeneration (AMD) is the leading cause of blindness in older people in developed countries. It has been suggested that heavy metal exposure may be associated with the development of AMD, but most studies have focused on the effec...

Privacy-Preserving Technology Using Federated Learning and Blockchain in Protecting against Adversarial Attacks for Retinal Imaging.

Ophthalmology
PURPOSE: Collaboration provides valuable data for robust artificial intelligence (AI) model development. Federated learning (FL) is a privacy-enhancing technology that allows collaboration while respecting privacy via the development of models withou...