AIMC Topic: Macular Degeneration

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Anti-VEGF treatment outcome prediction based on optical coherence tomography images in neovascular age-related macular degeneration using a deep neural network.

Scientific reports
Age-related macular degeneration (AMD) is a major cause of blindness in developed countries, and the number of affected patients is increasing worldwide. Intravitreal injections of anti-vascular endothelial growth factor (VEGF) are the standard thera...

Topographic and quantitative correlation of structure and function using deep learning in subclinical biomarkers of intermediate age-related macular degeneration.

Scientific reports
To examine the morphological impact of deep learning (DL)-quantified biomarkers on point-wise sensitivity (PWS) using microperimetry (MP) and optical coherence tomography (OCT) in intermediate AMD (iAMD). Patients with iAMD were examined by OCT (Spec...

Recent advances in the application of artificial intelligence in age-related macular degeneration.

BMJ open ophthalmology
Recent advancements in ophthalmology have been driven by the incorporation of artificial intelligence (AI), especially in diagnosing, monitoring treatment and predicting outcomes for age-related macular degeneration (AMD). AMD is a leading cause of i...

A Novel Management Challenge in Age-Related Macular Degeneration: Artificial Intelligence and Expert Prediction of Geographic Atrophy.

Ophthalmology. Retina
PURPOSE: The progression of geographic atrophy (GA) secondary to age-related macular degeneration is highly variable among individuals. Prediction of the progression is critical to identify patients who will benefit most from the first treatments cur...

Cross-instrument optical coherence tomography-angiography (OCTA)-based prediction of age-related macular degeneration (AMD) disease activity using artificial intelligence.

Scientific reports
This study investigates the efficacy of predicting age-related macular degeneration (AMD) activity through deep neural networks (DNN) using a cross-instrument training dataset composed of Optical coherence tomography-angiography (OCTA) images from tw...

Machine learning model for age-related macular degeneration based on heavy metals: The National Health and Nutrition Examination Survey 2005 to 2008.

Scientific reports
Age-related macular degeneration (AMD) is the leading cause of blindness in older people in developed countries. It has been suggested that heavy metal exposure may be associated with the development of AMD, but most studies have focused on the effec...

Privacy-Preserving Technology Using Federated Learning and Blockchain in Protecting against Adversarial Attacks for Retinal Imaging.

Ophthalmology
PURPOSE: Collaboration provides valuable data for robust artificial intelligence (AI) model development. Federated learning (FL) is a privacy-enhancing technology that allows collaboration while respecting privacy via the development of models withou...

AI in the clinical management of GA: A novel therapeutic universe requires novel tools.

Progress in retinal and eye research
Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a major breakthrough following failure of numerous previous trials. However, in the absen...

Empowering Portable Age-Related Macular Degeneration Screening: Evaluation of a Deep Learning Algorithm for a Smartphone Fundus Camera.

BMJ open
OBJECTIVES: Despite global research on early detection of age-related macular degeneration (AMD), not enough is being done for large-scale screening. Automated analysis of retinal images captured via smartphone presents a potential solution; however,...

Linking disease activity with optical coherence tomography angiography in neovascular age related macular degeneration using artificial intelligence.

Scientific reports
To investigate quantitative associations between AI-assessed disease activity and optical coherence tomography angiography (OCTA)-derived parameters in patients with neovascular age-related macular degeneration (nAMD) undergoing anti-VEGF therapy. OC...