AIMC Topic: Malaria, Falciparum

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Tile-based microscopic image processing for malaria screening using a deep learning approach.

BMC medical imaging
BACKGROUND: Manual microscopic examination remains the golden standard for malaria diagnosis. But it is laborious, and pathologists with experience are needed for accurate diagnosis. The need for computer-aided diagnosis methods is driven by the enor...

Application of machine and deep learning algorithms in optical microscopic detection of Plasmodium: A malaria diagnostic tool for the future.

Photodiagnosis and photodynamic therapy
Machine and deep learning techniques are prevalent in the medical discipline due to their high level of accuracy in disease diagnosis. One such disease is malaria caused by Plasmodium falciparum and transmitted by the female anopheles mosquito. Accor...

Predicting the impact of climate change on the re-emergence of malaria cases in China using LSTMSeq2Seq deep learning model: a modelling and prediction analysis study.

BMJ open
OBJECTIVES: Malaria is a vector-borne disease that remains a serious public health problem due to its climatic sensitivity. Accurate prediction of malaria re-emergence is very important in taking corresponding effective measures. This study aims to i...

Adaptive adversarial neural networks for the analysis of lossy and domain-shifted datasets of medical images.

Nature biomedical engineering
In machine learning for image-based medical diagnostics, supervised convolutional neural networks are typically trained with large and expertly annotated datasets obtained using high-resolution imaging systems. Moreover, the network's performance can...

Improving disaggregation models of malaria incidence by ensembling non-linear models of prevalence.

Spatial and spatio-temporal epidemiology
Maps of disease burden are a core tool needed for the control and elimination of malaria. Reliable routine surveillance data of malaria incidence, typically aggregated to administrative units, is becoming more widely available. Disaggregation regress...

Expert-level automated malaria diagnosis on routine blood films with deep neural networks.

American journal of hematology
Over 200 million malaria cases globally lead to half a million deaths annually. Accurate malaria diagnosis remains a challenge. Automated imaging processing approaches to analyze Thick Blood Films (TBF) could provide scalable solutions, for urban hea...

Machine learning analysis plans for randomised controlled trials: detecting treatment effect heterogeneity with strict control of type I error.

Trials
BACKGROUND: Retrospective exploratory analyses of randomised controlled trials (RCTs) seeking to identify treatment effect heterogeneity (TEH) are prone to bias and false positives. Yet the desire to learn all we can from exhaustive data measurements...

Detection of malaria parasites in dried human blood spots using mid-infrared spectroscopy and logistic regression analysis.

Malaria journal
BACKGROUND: Epidemiological surveys of malaria currently rely on microscopy, polymerase chain reaction assays (PCR) or rapid diagnostic test kits for Plasmodium infections (RDTs). This study investigated whether mid-infrared (MIR) spectroscopy couple...

Shift in Potential Malaria Transmission Areas in India, Using the Fuzzy-Based Climate Suitability Malaria Transmission (FCSMT) Model under Changing Climatic Conditions.

International journal of environmental research and public health
The future implications of climate change on malaria transmission at the global level have already been reported, however such evidences are scarce and limited in India. Here our study aims to assess, identify and map the potential effects of climate...

Identification of a Novel Clinical Phenotype of Severe Malaria using a Network-Based Clustering Approach.

Scientific reports
The parasite Plasmodium falciparum is the main cause of severe malaria (SM). Despite treatment with antimalarial drugs, more than 400,000 deaths are reported every year, mainly in African children. The diversity of clinical presentations associated w...