BACKGROUND: Malaria remains one the leading communicable causes of death. Approximately half of the world's population is considered at risk of infection, predominantly in African and South Asian countries. Although malaria is preventable, heterogene...
Convolutional neural networks (CNNs) provide flexible function approximations for a wide variety of applications when the input variables are in the form of images or spatial data. Although CNNs often outperform traditional statistical models in pred...
The Journal of the Association of Physicians of India
Nov 1, 2023
: To study the efficacy of pulse methylprednisolone (MPS) therapy in patients with malaria-associated acute respiratory distress syndrome (ARDS). : The study was a randomized, single-blind, placebo-controlled trial with a total sample size of 44 pati...
Timely and rapid diagnosis is crucial for faster and proper malaria treatment planning. Microscopic examination is the gold standard for malaria diagnosis, where hundreds of millions of blood films are examined annually. However, this method's effect...
BACKGROUND: The influence of rising global temperatures on malaria dynamics and distribution remains controversial, especially in central highland regions. We aimed to address this subject by studying the spatiotemporal heterogeneity of malaria and t...
MOTIVATION: Malaria, a mosquito-borne infectious disease affecting humans and other animals, is widespread in tropical and subtropical regions. Microscopy is the most common method for diagnosing the malaria parasite from stained blood smear samples....
Studies in health technology and informatics
May 27, 2021
Malaria is still a real public health concern in Sub-Saharan African countries such as Senegal where it represents approximately 35% of the consultation activities in the hospitals. This is mainly due to the lack of appropriate medical care support a...
The complex transmission ecologies of vector-borne and zoonotic diseases pose challenges to their control, especially in changing landscapes. Human incidence of zoonotic malaria ( Plasmodium knowlesi) is associated with deforestation although mechani...
BACKGROUND: Discovery of apicoplast as a drug target offers a new direction in the development of novel anti-malarial compounds, especially against the drug-resistant strains. Drugs such as azithromycin were reported to block the apicoplast developme...
Poor pharmacokinetic and toxicity profiles are major reasons for the low rate of advancing lead drug candidates into efficacy studies. The In-silico prediction of primary pharmacokinetic and toxicity properties in the drug discovery and development p...
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