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Mental Disorders

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Risk of data leakage in estimating the diagnostic performance of a deep-learning-based computer-aided system for psychiatric disorders.

Scientific reports
Deep-learning approaches with data augmentation have been widely used when developing neuroimaging-based computer-aided diagnosis (CAD) systems. To prevent the inflated diagnostic performance caused by data leakage, a correct cross-validation (CV) me...

Advancements in Drug Repurposing: Examples in Psychiatric Medications.

International journal of molecular sciences
Because there are a limited number of animal models for psychiatric diseases that can be extrapolated to humans, drug repurposing has been actively pursued. This study was aimed at uncovering recent trends in drug repurposing approaches and new techn...

New directions in psychiatric drug development: promising therapeutics in the pipeline.

Expert opinion on drug discovery
INTRODUCTION: Psychiatric disorders are a leading cause of disability worldwide, calling for an urgent need for new treatments, early detection, early intervention, and precision medicine. Drug discovery and development in psychiatry continues to exp...

Detecting individuals with severe mental illness using artificial intelligence applied to magnetic resonance imaging.

EBioMedicine
BACKGROUND: Identifying individuals at risk for severe mental illness (SMI) is crucial for prevention and early intervention strategies. While MRI shows potential for case identification even before illness onset, no practical model for mental health...

Sentiment analysis of clinical narratives: A scoping review.

Journal of biomedical informatics
A clinical sentiment is a judgment, thought or attitude promoted by an observation with respect to the health of an individual. Sentiment analysis has drawn attention in the healthcare domain for secondary use of data from clinical narratives, with a...

Depression Detection Based on Hybrid Deep Learning SSCL Framework Using Self-Attention Mechanism: An Application to Social Networking Data.

Sensors (Basel, Switzerland)
In today's world, mental health diseases have become highly prevalent, and depression is one of the mental health problems that has become widespread. According to WHO reports, depression is the second-leading cause of the global burden of diseases. ...

From promise to practice: towards the realisation of AI-informed mental health care.

The Lancet. Digital health
In this Series paper, we explore the promises and challenges of artificial intelligence (AI)-based precision medicine tools in mental health care from clinical, ethical, and regulatory perspectives. The real-world implementation of these tools is inc...

An End-to-End Human Abnormal Behavior Recognition Framework for Crowds With Mentally Disordered Individuals.

IEEE journal of biomedical and health informatics
Abnormal or violent behavior by people with mental disorders is common. When individuals with mental disorders exhibit abnormal behavior in public places, they may cause physical and mental harm to others as well as to themselves. Thus, it is necessa...

Construction of a Prediction Model for College Students' Psychological Disorders Based on Decision Systems and Improved Neural Networks.

Computational intelligence and neuroscience
Modeling and prediction of psychological disorders is a hot topic in current research. Neural networks are very important factors in improving the accuracy and precision ratios of the models which are developed for the prediction of the psychological...