For single-cell experiments, it is important to accurately count the number of viable cells in a nanoliter well. We used a deep learning-based convolutional neural network (CNN) on a large amount of digital data obtained as microscopic images. The tr...
IEEE transactions on neural networks and learning systems
Nov 22, 2017
Computerized microscopy image analysis plays an important role in computer aided diagnosis and prognosis. Machine learning techniques have powered many aspects of medical investigation and clinical practice. Recently, deep learning is emerging as a l...
Sickle cell disease (SCD) is a hematological disorder leading to blood vessel occlusion accompanied by painful episodes and even death. Red blood cells (RBCs) of SCD patients have diverse shapes that reveal important biomechanical and bio-rheological...
BACKGROUND AND OBJECTIVE: To diagnose infertility in men, semen analysis is conducted in which sperm morphology is one of the factors that are evaluated. Since manual assessment of sperm morphology is time-consuming and subjective, automatic classifi...
Oral Squamous Cell Carcinoma (OSCC) is a common type of cancer of the oral epithelium. Despite their high impact on mortality, sufficient screening methods for early diagnosis of OSCC often lack accuracy and thus OSCCs are mostly diagnosed at a late ...
BACKGROUND: The morphometric analysis of myelinated nerve fibers of peripheral nerves in cross-sectional optical microscopic images is valuable. Several automated methods for nerve fiber identification and segmentation have been reported. This paper ...
Morphological analysis is the standard method of assessing embryo quality; however, its inherent subjectivity tends to generate discrepancies among evaluators. Using genetic algorithms and artificial neural networks (ANNs), we developed a new method ...
Establishing early warning systems for anthrax attacks is crucial in biodefense. Despite numerous studies for decades, the limited sensitivity of conventional biochemical methods essentially requires preprocessing steps and thus has limitations to be...
IEEE reviews in biomedical engineering
Mar 22, 2017
Endomicroscopy is a new technique that allows human tissue to be characterized in vivo and in situ, circumventing the need for conventional biopsy and histology. Despite increased application and growing research interests in this area, the clinical ...
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