AIMC Topic: Middle Aged

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Immunodiagnostic plasma amino acid residue biomarkers detect cancer early and predict treatment response.

Nature communications
The immune response to tumour development is frequently targeted with therapeutics but remains largely unexplored in diagnostics, despite being stronger for early-stage tumours. We present an immunodiagnostic platform to detect this. We identify a pa...

The Helicobacter pylori AI-clinician harnesses artificial intelligence to personalise H. pylori treatment recommendations.

Nature communications
Helicobacter pylori (H. pylori) is the most common carcinogenic pathogen globally and the leading cause of gastric cancer. Here, we develop a reinforcement learning-based AI Clinician system to personalise treatment selection and evaluate its ability...

Finger drawing on smartphone screens enables early Parkinson's disease detection through hybrid 1D-CNN and BiGRU deep learning architecture.

PloS one
BACKGROUND: Parkinson's disease (PD), a progressive neurodegenerative disorder prevalent in aging populations, manifests clinically through characteristic motor impairments including bradykinesia, rigidity, and resting tremor. Early detection and tim...

Lay beliefs about AI assessment of interpersonal skills in personnel selection.

Scientific reports
Artificial intelligence (AI) is revolutionizing talent acquisition, with organizations increasingly replacing humans with AI technologies in personnel selection processes. Field studies of nurses provide preliminary evidence that AI can outperform hu...

Decoding depression: Event related potential dynamics and predictive neural signatures of depression severity.

Journal of affective disorders
Depression is a heterogeneous disorder marked by disruptions in cognitive and affective processing. While self-reported measures and clinical interviews remain the diagnostic standard, integrating objective neurophysiological markers could enhance as...

Deep learning algorithm for identifying osteopenia/osteoporosis using cervical radiography.

Scientific reports
Due to symptomatic gait imbalance and a high incidence of falls, patients with cervical disease-including degenerative cervical myelopathy-have a significantly increased risk of fragility fractures. To prevent such fractures in patients with cervical...

Identification of diagnostic biomarkers and dissecting immune microenvironment with crosstalk genes in the POAG and COVID-19 nexus.

Scientific reports
An underlying association between primary open-angle glaucoma (POAG) and COVID-19 has been hypothesized, but the causal link and shared mechanisms remain unclear. This study integrates epidemiological and bioinformatics approaches to investigate thei...

Development and validation of a machine learning-based nomogram for survival prediction of patients with hilar cholangiocarcinoma after curative-intent resection.

Scientific reports
Hilar cholangiocarcinoma (hCCA), a rare cancer of the biliary system, has a poor prognosis. This study aimed to investigate the risk factors affecting the survival of patients with hCCA after curative-intent resection and establish a survival predict...

Prediction of gastrointestinal hemorrhage in cardiology inpatients using an interpretable XGBoost model.

Scientific reports
Gastrointestinal bleeding (GIB) occurs more frequently in cardiovascular patients than in the general population, significantly affecting morbidity and mortality. However, existing predictive models often lack sufficient accuracy and interpretability...