AIMC Topic: Models, Biological

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Evaluating Computational Gene Ontology Annotations.

Methods in molecular biology (Clifton, N.J.)
Two avenues to understanding gene function are complementary and often overlapping: experimental work and computational prediction. While experimental annotation generally produces high-quality annotations, it is low throughput. Conversely, computati...

A Model of a Synthetic Biological Communication Interface between Mammalian Cells and Mechatronic Systems.

IEEE transactions on nanobioscience
The creation of communication interfaces between abiotic and biotic systems represents a significant research challenge. In this work, we design and model a system linking the biochemical signaling pathways of mammalian cells to the actions of a mobi...

Synthetic biology routes to bio-artificial intelligence.

Essays in biochemistry
The design of synthetic gene networks (SGNs) has advanced to the extent that novel genetic circuits are now being tested for their ability to recapitulate archetypal learning behaviours first defined in the fields of machine and animal learning. Here...

[A Fuzzy Logic Model-based Advisory System for Mechanical Ventilation].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
In the clinical practice,the mechanical ventilation is a very important assisting method to improve the patients’ breath.Whether or not the parameters set for the ventilator are correct would affect the pulmonary gas exchange.In this study,we try to ...

Multi-chip dataflow architecture for massive scale biophysically accurate neuron simulation.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
State-of-the-art neuron simulators are capable of simulating at most few tens/hundreds of neurons in real-time due to the exponential growth in the communication costs with the number of simulated neurons. In this paper, we present a novel, reconfigu...

Robot-assisted assessment of wrist proprioception: does wrist proprioceptive acuity follow Weber's law?

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Proprioception is essential for planning and controlling limb posture and movement. In our recent work, we introduced a standardized robot-aided method for measuring proprioceptive discrimination thresholds at the wrist to obtain reliable and accurat...

Design of a bio-inspired pneumatic artificial muscle with self-contained sensing.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Pneumatic artificial muscles (PAMs) are one of the most famous linear actuators in bio-inspired robotics. They can generate relatively high linear force considering their form factors and weights. Furthermore, PAMs are inexpensive compared with tradi...

A fuzzy logic controller based approach to model the switching mechanism of the mammalian central carbon metabolic pathway in normal and cancer cells.

Molecular bioSystems
Dynamics of large nonlinear complex systems, like metabolic networks, depend on several parameters. A metabolic pathway may switch to another pathway in accordance with the current state of parameters in both normal and cancer cells. Here, most of th...

Tail use improves performance on soft substrates in models of early vertebrate land locomotors.

Science (New York, N.Y.)
In the evolutionary transition from an aquatic to a terrestrial environment, early tetrapods faced the challenges of terrestrial locomotion on flowable substrates, such as sand and mud of variable stiffness and incline. The morphology and range of mo...

Modeling the thermotaxis behavior of C.elegans based on the artificial neural network.

Bioengineered
ASBTRACT This research aims at modeling the thermotaxis behavior of C.elegans which is a kind of nematode with full clarified neuronal connections. Firstly, this work establishes the motion model which can perform the undulatory locomotion with turni...