AIMC Topic: Molecular Sequence Annotation
Clear Filters Showing 131 to 140 of 260 articles
Improving tRNAscan-SE Annotation Results via Ensemble Classifiers.
Molecular informatics
Sep 14, 2015
tRNAScan-SE is a tRNA detection program that is widely used for tRNA annotation; however, the false positive rate of tRNAScan-SE is unacceptable for large sequences. Here, we used a machine learning method to try to improve the tRNAScan-SE results. A...
An empirical study of ensemble-based semi-supervised learning approaches for imbalanced splice site datasets.
BMC systems biology
Sep 1, 2015
BACKGROUND: Recent biochemical advances have led to inexpensive, time-efficient production of massive volumes of raw genomic data. Traditional machine learning approaches to genome annotation typically rely on large amounts of labeled data. The proce...
DNA-binding protein prediction using plant specific support vector machines: validation and application of a new genome annotation tool.
Nucleic acids research
Aug 24, 2015
There are currently 151 plants with draft genomes available but levels of functional annotation for putative protein products are low. Therefore, accurate computational predictions are essential to annotate genomes in the first instance, and to provi...
PPDB: A Tool for Investigation of Plants Physiology Based on Gene Ontology.
Interdisciplinary sciences, computational life sciences
Aug 23, 2015
Representing the way forward, from functional genomics and its ontology to functional understanding and physiological model, in a computationally tractable fashion is one of the ongoing challenges faced by computational biology. To tackle the standpo...
Application of comparative biology in GO functional annotation: the mouse model.
Mammalian genome : official journal of the International Mammalian Genome Society
Jul 4, 2015
The Gene Ontology (GO) is an important component of modern biological knowledge representation with great utility for computational analysis of genomic and genetic data. The Gene Ontology Consortium (GOC) consists of a large team of contributors incl...
TRAL: tandem repeat annotation library.
Bioinformatics (Oxford, England)
May 18, 2015
MOTIVATION: Currently, more than 40 sequence tandem repeat detectors are published, providing heterogeneous, partly complementary, partly conflicting results.
Machine learning applications in genetics and genomics.
Nature reviews. Genetics
May 7, 2015
The field of machine learning, which aims to develop computer algorithms that improve with experience, holds promise to enable computers to assist humans in the analysis of large, complex data sets. Here, we provide an overview of machine learning ap...
Deep convolutional neural networks for annotating gene expression patterns in the mouse brain.
BMC bioinformatics
May 7, 2015
BACKGROUND: Profiling gene expression in brain structures at various spatial and temporal scales is essential to understanding how genes regulate the development of brain structures. The Allen Developing Mouse Brain Atlas provides high-resolution 3-D...
Toll-like receptor signaling in vertebrates: testing the integration of protein, complex, and pathway data in the protein ontology framework.
PloS one
Apr 20, 2015
The Protein Ontology (PRO) provides terms for and supports annotation of species-specific protein complexes in an ontology framework that relates them both to their components and to species-independent families of complexes. Comprehensive curation o...
Computational algorithms to predict Gene Ontology annotations.
BMC bioinformatics
Apr 17, 2015
BACKGROUND: Gene function annotations, which are associations between a gene and a term of a controlled vocabulary describing gene functional features, are of paramount importance in modern biology. Datasets of these annotations, such as the ones pro...
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 32021
- Neural Networks, Computer 30231
- Algorithms 27405
- Deep Learning 26912
- Artificial Intelligence 24844
- Robotics 13389
- Image Processing, Computer-Assisted 9738
- Retrospective Studies 9346
- Magnetic Resonance Imaging 6347
- Reproducibility of Results 5670
- Tomography, X-Ray Computed 4866
- Support Vector Machine 4771
- Computational Biology 4333
- Brain 4129
- Computer Simulation 3935
Recent Journals
- Scientific reports 6800
- Sensors (Basel, Switzerland) 4794
- PloS one 4210
- Neural networks : the official journal of the International Neural Network Society 3026
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1916
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1378
- IEEE journal of biomedical and health informatics 1172
- Journal of chemical information and modeling 1066
- Nature communications 1047
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 874
- Journal of medical Internet research 864
- Briefings in bioinformatics 853