We introduce the first-ever statistical framework for estimating the age of Multiple Sclerosis (MS) lesions from magnetic resonance imaging (MRI). Estimating lesion age is an important step when studying the longitudinal behavior of MS lesions and ca...
Medical & biological engineering & computing
Jul 17, 2020
The segmentation of the lesion plays a core role in diagnosis and monitoring of multiple sclerosis (MS). Magnetic resonance imaging (MRI) is the most frequent image modality used to evaluate such lesions. Because of the massive amount of data, manual...
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
Jul 8, 2020
BACKGROUND: MR imaging is an essential component in managing patients with Multiple sclerosis (MS). This holds true for the initial diagnosis as well as for assessing the clinical course of MS. In recent years, a growing number of computer tools wer...
PURPOSE: The purpose of this study was to create an algorithm that combines multiple machine-learning techniques to predict the expanded disability status scale (EDSS) score of patients with multiple sclerosis at two years solely based on age, sex an...
The presence of cortical lesions in multiple sclerosis patients has emerged as an important biomarker of the disease. They appear in the earliest stages of the illness and have been shown to correlate with the severity of clinical symptoms. However, ...
Multiple sclerosis and related disorders
Jun 20, 2020
BACKGROUND: Increasing evidence for contribution of hemostasis components in multiple sclerosis (MS) has been reported. Hemostasis protein inhibitors display key regulatory roles, extending to regulation of innate immune response and inflammation, an...
Journal of neuroimaging : official journal of the American Society of Neuroimaging
May 26, 2020
BACKGROUND AND PURPOSE: Hereditary diffuse leukoencephalopathy with spheroids (HDLS) and multiple sclerosis (MS) are demyelinating and neurodegenerative disorders that can be hard to distinguish clinically and radiologically. HDLS is a rare disorder ...
Multiple sclerosis (Houndmills, Basingstoke, England)
May 22, 2020
OBJECTIVE: The aim of this study is to assess the performance of deep learning convolutional neural networks (CNNs) in segmenting gadolinium-enhancing lesions using a large cohort of multiple sclerosis (MS) patients.
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