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Multiple Sclerosis

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Big data and artificial intelligence applied to blood and CSF fluid biomarkers in multiple sclerosis.

Frontiers in immunology
Artificial intelligence (AI) has meant a turning point in data analysis, allowing predictions of unseen outcomes with precedented levels of accuracy. In multiple sclerosis (MS), a chronic inflammatory-demyelinating condition of the central nervous sy...

European cross-cultural neuropsychological test battery (CNTB) for the assessment of cognitive impairment in multiple sclerosis: Cognitive phenotyping and classification supported by machine learning techniques.

Multiple sclerosis and related disorders
BACKGROUND: The European Cross-Cultural Neuropsychological Test Battery (CNTB) has been proposed as a comprehensive battery for cognitive assessment, reducing the potential impact of cultural variables. In this validation study, we aimed to evaluate ...

Integrating large language models in care, research, and education in multiple sclerosis management.

Multiple sclerosis (Houndmills, Basingstoke, England)
Use of techniques derived from generative artificial intelligence (AI), specifically large language models (LLMs), offer a transformative potential on the management of multiple sclerosis (MS). Recent LLMs have exhibited remarkable skills in producin...

Disentangling Neurodegeneration From Aging in Multiple Sclerosis Using Deep Learning: The Brain-Predicted Disease Duration Gap.

Neurology
BACKGROUND AND OBJECTIVES: Disentangling brain aging from disease-related neurodegeneration in patients with multiple sclerosis (PwMS) is increasingly topical. The brain-age paradigm offers a window into this problem but may miss disease-specific eff...

Effectiveness of robotic rehabilitation for gait and balance in people with multiple sclerosis: a systematic review.

Journal of neurology
This review investigated the effectiveness of robotic-assisted gait training (RAGT) in improving gait and balance performance in adults with multiple sclerosis (MS). Databases and registers were searched from inception to December 2023 to identify ra...

MS Pattern Explorer: interactive visual exploration of temporal activity patterns for multiple sclerosis.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVES: This article describes the design and evaluation of MS Pattern Explorer, a novel visual tool that uses interactive machine learning to analyze fitness wearables' data. Applied to a clinical study of multiple sclerosis (MS) patients, the t...

Artificial neural network-based prediction of multiple sclerosis using blood-based metabolomics data.

Multiple sclerosis and related disorders
Multiple sclerosis (MS) remains a challenging neurological condition for diagnosis and management and is often detected in late stages, delaying treatment. Artificial intelligence (AI) is emerging as a promising approach to extracting MS information ...

AI-assisted assessment of fall risk in multiple sclerosis: A systematic literature review.

Multiple sclerosis and related disorders
BACKGROUND: Multiple sclerosis (MS) is an autoimmune disease that can increase the risk of falls in patients due to various factors. Traditional clinical assessments may not effectively identify those at risk of falling.

Higher effect sizes for the detection of accelerated brain volume loss and disability progression in multiple sclerosis using deep-learning.

Computers in biology and medicine
PURPOSE: Clinical validation of "BrainLossNet", a deep learning-based method for fast and robust estimation of brain volume loss (BVL) from longitudinal T1-weighted MRI, for the detection of accelerated BVL in multiple sclerosis (MS) and for the disc...