Bioorganic & medicinal chemistry letters
Jun 16, 2016
The present study describes the synthesis of two new series of 3-hydroxy-N-(4-oxo-2-phenyl-1,3-thiazinan-3-yl)-8-(trifluoromethyl)quinoline-2-carboxamide derivatives (4a-j) and 3-((7-chloroquinolin-4-ylamino)methyl)-2-phenyl-1,3-thiazinan-4-one deriv...
BACKGROUND: Tuberculous pericarditis is considered to be a paucibacillary process; the large pericardial fluid accumulation is attributed to an inflammatory response to tuberculoproteins. Mortality rates are high. We investigated the role of clinical...
International journal of mycobacteriology
Sep 5, 2015
OBJECTIVE/BACKGROUND: The latest incidence of tuberculosis (TB) (per 100,000 people) in Cameroon was 243.00 as of 2011. Over the past 21 years, the value for this indicator has fluctuated between 112.00 in 1990 and 320.00 in 2003. Worldwide, this inc...
Infra-species taxonomy is a prerequisite to compare features such as virulence in different pathogen lineages. Mycobacterium tuberculosis complex taxonomy has rapidly evolved in the last 20 years through intensive clinical isolation, advances in sequ...
A major hurdle facing tuberculosis (TB) investigators who want to utilize a rapidly growing body of data from both systems biology approaches and omics technologies is the lack of a standard vocabulary for data annotation and reporting. Lacking a mea...
International journal of mycobacteriology
Jun 25, 2015
BACKGROUND: A concentration of specimen is recommended for the effective recovery of Mycobacterium tuberculosis (MTB), but the bacteriological efficiency is not well evaluated. The present study evaluated the factors contributing to concentration eff...
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Oct 6, 2025
BACKGROUND: Coinfections of Mycobacterium tuberculosis (MTB) and human immunodeficiency virus (HIV) impose a substantial global health burden. Patients with MTB infection face a heightened risk of progression to incident active TB, which preventive t...
Tuberculosis (TB) remains a major global health challenge, particularly in low- and middle-income countries. Traditional microscopy-based diagnostics are labor-intensive and error-prone, while automated deep learning models often require detailed exp...
Mycobacteria, including (MTB) and non-tuberculosis mycobacteria (NTM), are important causes of infectious disease and cause significant mortality and morbidity globally. Fast detection is extremely important to reduce transmission and mortality asso...
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
Jul 12, 2025
Tuberculosis (TB) remains a significant global public health threat. Achieving the 2035 target for TB elimination requires interrupting its community transmission, which depends critically on enhancing case detection. Active screening for TB in commu...
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