AIMC Topic: Mycoses

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Recent research frontiers of heterocycles as antifungal Agents: Insights from the past five years.

European journal of medicinal chemistry
This review explores the growing global concern of fungal infections, particularly in immunocompromised individuals, and highlights the critical need for improved antifungal therapies. With the rise of multidrug-resistant strains, such as Candida aur...

Development of machine learning models to predict the risk of fungal infection following flexible ureteroscopy lithotripsy.

BMC medical informatics and decision making
BACKGROUND: The flexible ureteroscopy lithotripsy (F-URL) is an important treatment for upper urinary tract stones. However, urolithiasis, surgical procedures, and catheter placement are risk factors for fungal infections. Our study aimed to construc...

Early differential diagnosis models of Talaromycosis and Tuberculosis in HIV-negative hosts using clinical data and machine learning.

Journal of infection and public health
BACKGROUND: Talaromyces marneffei is an emerging pathogen, and the number of infections in HIV-negative individuals is increasing. In HIV-negative individuals, talaromycosis is usually misdiagnosed as another disease, especially tuberculosis (TB).

Leveraging machine learning to uncover multi-pathogen infection dynamics across co-distributed frog families.

PeerJ
BACKGROUND: Amphibians are experiencing substantial declines attributed to emerging pathogens. Efforts to understand what drives patterns of pathogen prevalence and differential responses among species are challenging because numerous factors related...

The accuracy of deep learning models for diagnosing maxillary fungal ball rhinosinusitis.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
PURPOSE: To assess the accuracy of deep learning models for the diagnosis of maxillary fungal ball rhinosinusitis (MFB) and to compare the accuracy, sensitivity, specificity, precision, and F1-score with a rhinologist.

iAFPs-Mv-BiTCN: Predicting antifungal peptides using self-attention transformer embedding and transform evolutionary based multi-view features with bidirectional temporal convolutional networks.

Artificial intelligence in medicine
Globally, fungal infections have become a major health concern in humans. Fungal diseases generally occur due to the invading fungus appearing on a specific portion of the body and becoming hard for the human immune system to resist. The recent emerg...

Scedosporium boydii finding in an immunocompromised patient and review of the literature.

Revista iberoamericana de micologia
BACKGROUND: Scedosporiasis is an emerging mycosis that has gained importance in recent years due to its worldwide prevalence. It is caused by species of the Scedosporium apiospermum complex. These species can cause opportunistic infections in immunoc...

Artificial Intelligence: Exploring utility in detection and typing of fungus with futuristic application in fungal cytology.

Cytopathology : official journal of the British Society for Clinical Cytology
Artificial Intelligence (AI) is an emerging, transforming and revolutionary technology that has captured attention worldwide. It is translating research into precision oncology treatments. AI can analyse large or big data sets requiring high-speed sp...

Application of deep learning algorithm in the recognition of cryptococcosis and talaromycosis skin lesions.

Mycoses
BACKGROUND: Cryptococcosis and talaromycosis are known as 'neglected epidemics' due to their high case fatality rates and low concern. Clinically, the skin lesions of the two fungal diseases are similar and easily misdiagnosed. Therefore, this study ...

Coupling machine learning and epidemiological modelling to characterise optimal fungicide doses when fungicide resistance is partial or quantitative.

Journal of the Royal Society, Interface
Increasing fungicide dose tends to lead to better short-term control of plant diseases. However, high doses select more rapidly for fungicide resistant strains, reducing long-term disease control. When resistance is qualitative and complete-i.e. resi...