AIMC Topic: Mycotoxins

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Molecularly imprinted polymers for mycotoxin biosensing: Rational design, advanced applications, and future horizons.

Biosensors & bioelectronics
Molecularly imprinted polymers (MIPs) have emerged as transformative synthetic receptors for mycotoxin detection, addressing critical global food safety challenges through their exceptional stability and design flexibility. This review systematically...

Lactic acid bacteria as promising dietary-derived bioadsorbents for foodborne contaminants: Mechanism, application advances and future perspectives.

Food chemistry
Foodborne contaminants, such as mycotoxins and microplastics, pose significant threats to human health due to their high toxicity and persistence in the food chain, thus necessitate effective mitigation strategies. Lactic acid bacteria (LAB), charact...

Recent Development of Methods and Techniques in the Detection of Mycotoxins in Agricultural Products.

Journal of agricultural and food chemistry
Mycotoxins are produced by fungi and possess cytotoxic properties that cause extensive cellular damage. Mycotoxins pose a significant threat to the harvesting and storage of crops as well as potential carcinogenic, teratogenic, and mutagenic risks to...

Exploring Hidden Dangers: Predicting Mycotoxin-like Toxicity and Mapping Toxicological Networks in Hepatocellular Carcinoma.

Journal of chemical information and modeling
Mycotoxins are potent triggers of hepatocellular carcinoma (HCC) due to their intricate interplay with cellular macromolecules and signaling pathways. This study integrates machine learning and biomolecular analyses to elucidate the mechanisms underl...

Machine Learning-Assisted Multiplexed Fluorescence-Labeled miRNAs Imaging Decoding for Combined Mycotoxins Toxicity Assessment.

Analytical chemistry
Mycotoxins, particularly deoxynivalenol (DON) and zearalenone (ZEN), are common food contaminants that frequently co-occur in grains, posing significant health risks. This study proposed a multiplexed detection platform for simultaneous quantificatio...

Enhancing the application of near-infrared spectroscopy in grain mycotoxin detection: An exploration of a transfer learning approach across contaminants and grains.

Food chemistry
Cereals are a primary source of sustenance for humanity. Monitoring, controlling, and preventing mycotoxins in cereals are vital for ensuring the safety of the cereals and their derived products. This study introduces transfer learning strategies int...

Structural Similarity, Activity, and Toxicity of Mycotoxins: Combining Insights from Unsupervised and Supervised Machine Learning Algorithms.

Journal of agricultural and food chemistry
A large number of mycotoxins and related fungal metabolites have not been assessed in terms of their toxicological impacts. Current methodologies often prioritize specific target families, neglecting the complexity and presence of co-occurring compou...

Dual-Mode Colorimetric/SERS Lateral Flow Immunoassay with Machine Learning-Driven Optimization for Ultrasensitive Mycotoxin Detection.

Analytical chemistry
Detecting and quantifying mycotoxins using LFIA are challenging due to the need for high sensitivity and accuracy. To address this, a dual-mode colorimetric-SERS LFIA was developed for detecting deoxynivalenol (DON). Rhodium nanocores provided strong...

Microfluidic Optical Aptasensor for Small Molecules Based on Analyte-Tuned Growth of Gold Nanoseeds and Machine Learning-Enhanced Spectrum Analysis: Rapid Detection of Mycotoxins.

ACS sensors
Natural toxins, mainly small molecules, are a category of chemical hazards in agri-food systems that pose threats to both public health and food security. Current standard methods for monitoring these toxins, predominantly based on liquid chromatogra...

Machine learning driven metal oxide-based portable sensor array for on-site detection and discrimination of mycotoxins in corn sample.

Food chemistry
Cereals, grains, and feedstuffs are prone to contamination by fungi during various stages from growth to storage. These fungi may produce harmful mycotoxins impacting food quality and safety. Thus, the development of quick and reliable methods for on...