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Flexible modulation of sequence generation in the entorhinal-hippocampal system.

Nature neuroscience
Exploration, consolidation and planning depend on the generation of sequential state representations. However, these algorithms require disparate forms of sampling dynamics for optimal performance. We theorize how the brain should adapt internally ge...

Large-scale nonlinear Granger causality for inferring directed dependence from short multivariate time-series data.

Scientific reports
A key challenge to gaining insight into complex systems is inferring nonlinear causal directional relations from observational time-series data. Specifically, estimating causal relationships between interacting components in large systems with only s...

A biomimetic neural encoder for spiking neural network.

Nature communications
Spiking neural networks (SNNs) promise to bridge the gap between artificial neural networks (ANNs) and biological neural networks (BNNs) by exploiting biologically plausible neurons that offer faster inference, lower energy expenditure, and event-dri...

Analysis of the human connectome data supports the notion of a "Common Model of Cognition" for human and human-like intelligence across domains.

NeuroImage
The Common Model of Cognition (CMC) is a recently proposed, consensus architecture intended to capture decades of progress in cognitive science on modeling human and human-like intelligence. Because of the broad agreement around it and preliminary ma...

Examining the Coding Strength of Object Identity and Nonidentity Features in Human Occipito-Temporal Cortex and Convolutional Neural Networks.

The Journal of neuroscience : the official journal of the Society for Neuroscience
A visual object is characterized by multiple visual features, including its identity, position and size. Despite the usefulness of identity and nonidentity features in vision and their joint coding throughout the primate ventral visual processing pat...

Brain tissues have single-voxel signatures in multi-spectral MRI.

NeuroImage
Since the seminal works by Brodmann and contemporaries, it is well-known that different brain regions exhibit unique cytoarchitectonic and myeloarchitectonic features. Transferring the approach of classifying brain tissues - and other tissues - based...

Interaction of Indirect and Hyperdirect Pathways on Synchrony and Tremor-Related Oscillation in the Basal Ganglia.

Neural plasticity
Low-frequency oscillatory activity (3-9 Hz) and increased synchrony in the basal ganglia (BG) are recognized to be crucial for Parkinsonian tremor. However, the dynamical mechanism underlying the tremor-related oscillations still remains unknown. In ...

Predicting Parkinson's disease trajectory using clinical and neuroimaging baseline measures.

Parkinsonism & related disorders
INTRODUCTION: Predictive biomarkers of Parkinson's Disease progression are needed to expedite neuroprotective treatment development and facilitate prognoses for patients. This work uses measures derived from resting-state functional magnetic resonanc...

Machine learning-based classification of mitochondrial morphology in primary neurons and brain.

Scientific reports
The mitochondrial network continually undergoes events of fission and fusion. Under physiologic conditions, the network is in equilibrium and is characterized by the presence of both elongated and punctate mitochondria. However, this balanced, homeos...

Dynamics of a Large-Scale Spiking Neural Network with Quadratic Integrate-and-Fire Neurons.

Neural plasticity
Since the high dimension and complexity of the large-scale spiking neural network, it is difficult to research the network dynamics. In recent decades, the mean-field approximation has been a useful method to reduce the dimension of the network. In t...