In probabilistic reversal learning, the choice option yielding reward with higher probability switches at a random trial. To perform optimally in this task, one has to accumulate evidence across trials to infer the probability that a reversal has occ...
Alterations in brain connectivity provide early indications of neurodegenerative diseases like Alzheimer's disease (AD). Here, we present a novel framework that integrates a Hidden Markov Model (HMM) within the architecture of a convolutional neural ...
Advances in brain stimulation have made it possible to target smaller and smaller regions for electromagnetic stimulation, in the hopes of producing increasingly focal neural effects. However, the brain is extensively interconnected, and the neurons ...
Identifying the computational roles of different neuron families is crucial for understanding neural networks. Most neural diversity is embodied in various types of γ-aminobutyric acid-mediated (GABAergic) interneurons, grouped into four major famili...
Achieving a deep understanding of brain mechanisms requires multi-scale perspectives to capture the architecture of complex networks. In this study, we focused on patients with cognitive impairment and constructed individual brain networks from neuro...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sep 3, 2025
Cerebellum (CB) interactions with forebrain systems contribute to learning cognitive and motor tasks, but the nature of these interactions is unknown. Trace eyeblink conditioning (EBC) is an excellent associative learning paradigm for examining inter...
Emotion regulation plays a crucial role in mental health, and difficulties in regulating emotions can contribute to psychological disorders. While reappraisal and suppression are well-studied strategies, the joint contributions of gray matter (GM) an...
Proceedings of the National Academy of Sciences of the United States of America
Aug 28, 2025
Human learning embodies a striking duality: Sometimes, we can rapidly infer and compose logical rules, benefiting from structured curricula (e.g., in formal education), while other times, we rely on an incremental approach or trial-and-error, learnin...
Cognitive behavioral therapy (CBT) and pharmacotherapy are primary treatments for major depressive disorder (MDD). However, their differential effects on the neural networks associated with rumination, or repetitive negative thinking, remain poorly u...
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