International journal of molecular sciences
May 26, 2025
The active sites of enzymes are able to activate substrates and perform chemical reactions that cannot occur in solutions. We focus on the hydrolysis reactions catalyzed by enzymes and initiated by the nucleophilic attack of the substrate's carbonyl ...
Engineered T-cell receptor (eTCR) systems rely on accurately generated T-cell receptor (TCR) sequences to enhance immunotherapy predictability and efficacy. The most variable and crucial part of the TCR receptor is the CDR3 sequence region. Current m...
Due to the diverse molecular structures of chemical compounds and their intricate biological pathways of toxicity, predicting their reproductive and developmental toxicity remains a challenge. Traditional Quantitative Structure-Activity Relationship ...
BACKGROUND: Individuals with patellofemoral pain (PFP) present mechanical disorders during functional tests and activities. Studies often evaluate this population to understand the relationship between mechanical factors and pain/malalignment. This s...
Skin cancer is one of the most prevalent malignant tumors, and early detection is crucial for patient prognosis, leading to the development of mobile applications as screening tools. Recent advances in deep neural networks (DNNs) have accelerated the...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
May 23, 2025
Accurate and efficient segmentation of medical images plays a vital role in clinical tasks, such as diagnostic procedures and planning treatments. Traditional U-shaped encoder-decoder architectures, built on convolutional and transformer-based networ...
Post-COVID-19, depression rates have risen sharply, increasing the need for early diagnosis using electroencephalogram (EEG) and deep learning. To tackle this, we developed a cloud-based computer-aided depression diagnostic (CCADD) system that utiliz...
Sign languages are essential for communication among over 430 million deaf and hard-of-hearing individuals worldwide. However, recognizing Arabic Sign Language (ArSL) in real-world settings remains challenging due to issues like background noise, lig...
Deep learning-based methods for identifying and tracking cells within microscopy images have revolutionized the speed and throughput of data analysis. These methods for analyzing biological and medical data have capitalized on advances from the broad...
Children often learn the meanings of nouns before they grasp the meanings of verbs. This discrepancy could arise from differences in the complexity of visual characteristics for categories that language describes, the inherent structure of language, ...
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