AIMC Topic: Organs at Risk

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Application of deep learning to auto-delineation of target volumes and organs at risk in radiotherapy.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
The technological advancement heralded the arrival of precision radiotherapy (RT), thereby increasing the therapeutic ratio and decreasing the side effects from treatment. Contour of target volumes (TV) and organs at risk (OARs) in RT is a complicate...

Deep learning model for automatic contouring of cardiovascular substructures on radiotherapy planning CT images: Dosimetric validation and reader study based clinical acceptability testing.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Large radiotherapy (RT) planning imaging datasets with consistently contoured cardiovascular structures are essential for robust cardiac radiotoxicity research in thoracic cancers. This study aims to develop and validate a hig...

Evaluation of deep learning-based autosegmentation in breast cancer radiotherapy.

Radiation oncology (London, England)
PURPOSE: To study the performance of a proposed deep learning-based autocontouring system in delineating organs at risk (OARs) in breast radiotherapy with a group of experts.

Outcome-based multiobjective optimization of lymphoma radiation therapy plans.

The British journal of radiology
At its core, radiation therapy (RT) requires balancing therapeutic effects against risk of adverse events in cancer survivors. The radiation oncologist weighs numerous disease and patient-level factors when considering the expected risk-benefit ratio...

Automatic radiotherapy delineation quality assurance on prostate MRI with deep learning in a multicentre clinical trial.

Physics in medicine and biology
Volume delineation quality assurance (QA) is particularly important in clinical trial settings where consistent protocol implementation is required, as outcomes will affect future as well current patients. Currently, where feasible, this is conducted...

The impact of training sample size on deep learning-based organ auto-segmentation for head-and-neck patients.

Physics in medicine and biology
To investigate the impact of training sample size on the performance of deep learning-based organ auto-segmentation for head-and-neck cancer patients, a total of 1160 patients with head-and-neck cancer who received radiotherapy were enrolled in this ...

Evaluation of auto-segmentation accuracy of cloud-based artificial intelligence and atlas-based models.

Radiation oncology (London, England)
BACKGROUND: Contour delineation, a crucial process in radiation oncology, is time-consuming and inaccurate due to inter-observer variation has been a critical issue in this process. An atlas-based automatic segmentation was developed to improve the d...

Deep learning method for prediction of patient-specific dose distribution in breast cancer.

Radiation oncology (London, England)
BACKGROUND: Patient-specific dose prediction improves the efficiency and quality of radiation treatment planning and reduces the time required to find the optimal plan. In this study, a patient-specific dose prediction model was developed for a left-...

Clinical implementation of deep-learning based auto-contouring tools-Experience of three French radiotherapy centers.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Deep-learning (DL)-based auto-contouring solutions have recently been proposed as a convincing alternative to decrease workload of target volumes and organs-at-risk (OAR) delineation in radiotherapy planning and improve inter-observer consistency. Ho...