AIMC Topic: Organs at Risk

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Prior knowledge of anatomical relationships supports automatic delineation of clinical target volume for cervical cancer.

Scientific reports
Deep learning has been used for automatic planning of radiotherapy targets, such as inferring the clinical target volume (CTV) for a given new patient. However, previous deep learning methods mainly focus on predicting CTV from CT images without cons...

Beam orientation optimization in IMRT using sparse mixed integer programming and non-convex fluence map optimization.

Physics in medicine and biology
Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is a complex, non-convex problem traditionally addressed with heuristic methods.This work demonstrates the potential improvement of the proposed BOO, providing a math...

Quantitative and automatic plan-of-the-day assessment to facilitate adaptive radiotherapy in cervical cancer.

Physics in medicine and biology
To facilitate implementation of plan-of-the-day (POTD) selection for treating locally advanced cervical cancer (LACC), we developed a POTD assessment tool for CBCT-guided radiotherapy (RT). A female pelvis segmentation model (U-Seg3) is combined with...

Evaluation of deliverable artificial intelligence-based automated volumetric arc radiation therapy planning for whole pelvic radiation in gynecologic cancer.

Scientific reports
This study aimed to develop a deep learning (DL)-based deliverable whole pelvic volumetric arc radiation therapy (VMAT) for patients with gynecologic cancer using a prototype DL-based automated planning support system, named RatoGuide, to evaluate it...

Contouring in transition: perceptions of AI-based autocontouring by radiation oncologists and medical physicists in German-speaking countries.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
BACKGROUND: Artificial intelligence (AI)-based autocontouring software has the potential to revolutionize radiotherapy planning. In recent years, several AI-based autocontouring solutions with many advantages have emerged; however, their clinical use...

Using deep learning generated CBCT contours for online dose assessment of prostate SABR treatments.

Journal of applied clinical medical physics
Prostate Stereotactic Ablative Body Radiotherapy (SABR) is an ultra-hypofractionated treatment where small setup errors can lead to higher doses to organs at risk (OARs). Although bowel and bladder preparation protocols reduce inter-fraction variabil...

Reinforcement learning-driven automated head and neck simultaneous integrated boost (SIB) radiation therapy: flexible treatment planning aligned with clinical preferences.

Physics in medicine and biology
Head-and-neck simultaneous integrated boost (SIB) treatment planning using intensity modulated radiation therapy is particularly challenging due to the proximity to organs-at-risk. Depending on the specific clinical conditions, different parotid-spar...

Towards improved prescription metrics in novel radiotherapy techniques: a machine learning study.

Physics in medicine and biology
FLASH radiotherapy (RT), microbeam RT (MRT) and minibeam RT (MBRT) are novel RT techniques that have been shown to reduce normal tissue complication probabilities, by modulating the dose distributions through different parameters in space and time. T...

Evaluating the dosimetric and positioning accuracy of a deep learning based synthetic-CT model for liver radiotherapy treatment planning.

Biomedical physics & engineering express
An MRI-only workflow requires synthetic computed tomography (sCT) images to enable dose calculation. This study evaluated the dosimetric and patient positioning accuracy of deep learning-generated sCT for liver radiotherapy.sCT images were generated ...

Open-source deep-learning models for segmentation of normal structures for prostatic and gynecological high-dose-rate brachytherapy: Comparison of architectures.

Journal of applied clinical medical physics
BACKGROUND: The use of deep learning-based auto-contouring algorithms in various treatment planning services is increasingly common. There is a notable deficit of commercially or publicly available models trained on large or diverse datasets containi...