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Osteoporosis

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A study on whether deep learning models based on CT images for bone density classification and prediction can be used for opportunistic osteoporosis screening.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
UNLABELLED: This study utilized deep learning to classify osteoporosis and predict bone density using opportunistic CT scans and independently tested the models on data from different hospitals and equipment. Results showed high accuracy and strong c...

Validation of bone mineral density measurement using quantitative CBCT image based on deep learning.

Scientific reports
The bone mineral density (BMD) measurement is a direct method of estimating human bone mass for diagnosing osteoporosis, and performed to objectively evaluate bone quality before implant surgery in dental clinics. The objective of this study was to v...

Generalizability of Deep Learning Classification of Spinal Osteoporotic Compression Fractures on Radiographs Using an Adaptation of the Modified-2 Algorithm-Based Qualitative Criteria.

Academic radiology
RATIONALE AND OBJECTIVES: Spinal osteoporotic compression fractures (OCFs) can be an early biomarker for osteoporosis but are often subtle, incidental, and underreported. To ensure early diagnosis and treatment of osteoporosis, we aimed to build a de...

Prediction of osteoporosis using MRI and CT scans with unimodal and multimodal deep-learning models.

Diagnostic and interventional radiology (Ankara, Turkey)
PURPOSE: Osteoporosis is the systematic degeneration of the human skeleton, with consequences ranging from a reduced quality of life to mortality. Therefore, the prediction of osteoporosis reduces risks and supports patients in taking precautions. De...

Deep-Learning-Based Detection of Vertebral Fracture and Osteoporosis Using Lateral Spine X-Ray Radiography.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Osteoporosis and vertebral fractures (VFs) remain underdiagnosed. The addition of deep learning methods to lateral spine radiography (a simple, widely available, low-cost test) can potentially solve this problem. In this study, we develop deep learni...

Automated, calibration-free quantification of cortical bone porosity and geometry in postmenopausal osteoporosis from ultrashort echo time MRI and deep learning.

Bone
BACKGROUND: Assessment of cortical bone porosity and geometry by imaging in vivo can provide useful information about bone quality that is independent of bone mineral density (BMD). Ultrashort echo time (UTE) MRI techniques of measuring cortical bone...

Advances in materials-based therapeutic strategies against osteoporosis.

Biomaterials
Osteoporosis is caused by the disruption in homeostasis between bone formation and bone resorption. Conventional management of osteoporosis involves systematic drug administration and hormonal therapy. These treatment strategies have limited curative...

Interpretable Deep-Learning Approaches for Osteoporosis Risk Screening and Individualized Feature Analysis Using Large Population-Based Data: Model Development and Performance Evaluation.

Journal of medical Internet research
BACKGROUND: Osteoporosis is one of the diseases that requires early screening and detection for its management. Common clinical tools and machine-learning (ML) models for screening osteoporosis have been developed, but they show limitations such as l...

Predicting the risk of osteoporosis in older Vietnamese women using machine learning approaches.

Scientific reports
Osteoporosis contributes significantly to health and economic burdens worldwide. However, the development of osteoporosis-related prediction tools has been limited for lower-middle-income countries, especially Vietnam. This study aims to develop pred...

Application of Deep Convolutional Neural Networks in the Diagnosis of Osteoporosis.

Sensors (Basel, Switzerland)
The aim of this study was to assess the possibility of using deep convolutional neural networks (DCNNs) to develop an effective method for diagnosing osteoporosis based on CT images of the spine. The research material included the CT images of L1 spo...