BMC medical informatics and decision making
Oct 15, 2025
BACKGROUND: Cognitive impairment is a prominent non-motor manifestation of Parkinson's disease (PD) and is associated with reduced quality of life, increased mortality, and higher healthcare utilization. We aimed to develop and externally validate a ...
BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder that affects both motor and cognitive functions, particularly working memory (WM). Machine learning offers an advantage for decoding complex brain activity patterns, but its applica...
Parkinson's disease (PD) is a prevalent and complex neurodegenerative disorder, with early diagnosis playing a critical role in timely treatment and management. Handwriting dynamics has emerged as a promising biomarker for early detection of PD, yet ...
To develop applications for assisting Parkinson's disease (PD) patients, extracting Parkinsonian tremors from the raw signal is crucial; however, conventional methods such as filtering require a preset frequency range, and a poorly set frequency rang...
Parkinson's disease (PD) is a progressive neurodegenerative disorder that remained challenging for proper diagnosis in its early stages due to its heterogeneous symptom presentation and overlapping clinical features. Consequently, there is no consens...
Parkinson's disease (PD) is a chronic neurodegenerative disorder characterized by progressive loss of dopaminergic neurons in substantia nigra, resulting in both motor impairments and cognitive decline. Traditional PD classification methods are exper...
Parkinson's disease (PD), the second most prevalent neurodegenerative disorder, remains challenging to diagnose at its earliest stages due to the absence of definitive biomarkers and overlapping clinical features with other synucleinopathies, thereby...
Phytomedicine : international journal of phytotherapy and phytopharmacology
Sep 15, 2025
BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder with increasing global prevalence. Chaihu-shugan-san (CSS) is a Chinese medicine compound with reported neuroprotective properties. However, the precise bioactive consti...
Subthalamic deep brain stimulation (STN-DBS) provides unprecedented spatiotemporal precision for the treatment of Parkinson's disease (PD), allowing for direct real-time state-specific adjustments. Inspired by findings from optogenetic stimulation in...
Speech disorders differ between Parkinson's disease (PD) and multiple system atrophy (MSA), but studies focusing on group differences based on syllables or including cerebellar ataxia (CA) are lacking until now. This cross-sectional study aimed to an...
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