AIMC Topic: Peroxisome Proliferator-Activated Receptors

Clear Filters Showing 1 to 4 of 4 articles

Exposure to nitrate induces alterations in blood parameter responses, liver immunity, and lipid metabolism in juvenile turbot (Scophthalmus maximus).

Aquatic toxicology (Amsterdam, Netherlands) Aug 24, 2022
Nitrate (NO) pollution of waterbodies has attracted significant global attention as it poses a serious threat to aquatic organisms and human beings. This study aimed to evaluate the role of NO, an end product of biological nitrification processes, in...
Liver X Receptors Muramidase Complement C4 Nitrates Carnitine O-Palmitoyltransferase Heat-Shock Proteins Peroxisome Proliferator-Activated Receptors Animals Aspartate Aminotransferases Flatfishes Liver RNA, Messenger Alanine Transaminase Sterol Regulatory Element Binding Protein 1 Lipid Metabolism Complement C3 Water Pollutants, Chemical Fish Proteins Humans Immunoglobulin M Tumor Necrosis Factor-alpha
View on PubMed DOI

De Novo Design of Bioactive Small Molecules by Artificial Intelligence.

Molecular informatics Jan 10, 2018
Generative artificial intelligence offers a fresh view on molecular design. We present the first-time prospective application of a deep learning model for designing new druglike compounds with desired activities. For this purpose, we trained a recurr...
Molecular Docking Simulation Deep Learning HEK293 Cells Humans Small Molecule Libraries Drug Design Retinoid X Receptors Peroxisome Proliferator-Activated Receptors Quantitative Structure-Activity Relationship
View on PubMed DOI

Bioinformatics approach reveals systematic mechanism underlying lung adenocarcinoma.

Tumori May 21, 2015
BACKGROUND: The purpose of this work was to explore the systematic molecular mechanism of lung adenocarcinoma and gain a deeper insight into it.
Gene Expression Regulation, Neoplastic Membrane Proteins Computational Biology Calcium Peroxisome Proliferator-Activated Receptors Adenocarcinoma Signal Transduction Software Humans Lung Neoplasms Gene Expression Profiling Receptor Cross-Talk Collagen Type X Gene Ontology Protein Array Analysis Adenocarcinoma of Lung
View on PubMed DOI

[Alpinetin promotes the binding of PPAR and methyltransferase].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology Dec 1, 2017
Objective To screen the nucleus located-methyltransferase in murine macrophages (RAW246.7 cells) after peroxisome proliferator-activated receptors (PPAR) is activated by alpinetin so as to prove the epigenetic modification effect of alpinetin. Method...
Anilides Animals Computational Biology Peroxisome Proliferator-Activated Receptors Mice Cells, Cultured Methyltransferases Cell Nucleus Flavanones
View on PubMed
Popular Topics
Recent Journals