AIMC Topic: Plant Extracts

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Unveiling potent xanthine oxidase inhibitors in two Balanophora spp. using machine learning-based virtual screening and molecular docking approach.

Scientific reports
Pharmacological studies revealed that the Balanophora species contains diverse phytochemicals which enable interesting biological activities and emphasize their pharmaceutical relevance. Previously, we identified significant xanthine oxidase (XO) inh...

Artificial intelligence-assisted optimization of extraction enhances the biological activity of Phylloporia ribis.

Scientific reports
This research focuses on enhancing the extraction efficiency of Phylloporia ribis and assessing its biological functions. Key parameters including extraction temperature, duration, and ethanol-to-water ratio were optimized through both Response Surfa...

Bioactive compound identification without fractionation: an Ocimum spp. case study.

Metabolomics : Official journal of the Metabolomic Society
INTRODUCTION: Identifying the phytochemistry underpinning a plant's observed therapeutic benefits is essential for understanding mechanisms of action and developing novel therapeutics. More recent efforts fusing global metabolomics and multivariate p...

Multidimensional component quantitative analysis: Exploring commercial mango cultivars in China.

Food chemistry
Different mango cultivars exhibit distinct characteristics in food quality and nutraceutical value, influencing both market potential and consumer preference. We hypothesized that genotype-driven variation in metabolites underpins these quality diffe...

Evaluation of antioxidant, anticholinesterase and antiproliferative potential of Artemisia herba-alba by artificial intelligence-assisted extraction optimization.

Scientific reports
In this study, in order to maximize the biological activity of Artemisia herba-alba Asso, extraction conditions were optimized by two different methods: Response Surface Methodology (RSM) and Artificial Neural Network-Genetic Algorithm (ANN-GA). A to...

Artificial neural network optimized green synthesis of cysteine-conjugated silver nanoparticles for antibacterial activity against staphylococcus nepalensis to combat cystitis.

Antonie van Leeuwenhoek
The emergence of multidrug-resistant pathogens has increased the urgency for alternative treatment options for infections like cystitis. This study focused on the green synthesis of silver nanoparticles and cysteine-conjugated silver nanoparticles ut...

Deep learning-based fine-tuning transfer improves the generalizability of tea component prediction using miniature near-infrared spectroscopy.

Food chemistry
Model accuracies for predicting tea components using near-infrared spectroscopy are often constrained by sample type. Herein, spectral data from four tea types (green, black, oolong, and yellow) were collected using a low-cost, miniature near-infrare...

Glabridin from L. Exhibits Anti-Triple-Negative Breast Cancer Effects by Regulating Various Cell Cycle Genes.

Journal of agricultural and food chemistry
Glabridin (GLA), a characteristic polyphenolic extracted from the renowned sweet plant L., demonstrates potent anticancer effects. This study aims to investigate the effects of GLA on triple-negative breast cancer (TNBC) and its underlying mechanisms...

Sustainable and novel approaches for bioactive compound extraction: Development of hydrodynamic cavitation and coupled machine learning-spline techniques for Ascophyllum nodosum and Fucus vesiculosus.

Food chemistry
Ascophyllum nodosum and Fucus vesiculosus brown seaweeds are rich in polyphenols, phlorotannins, proteins, and antioxidants, valuable in the food, pharmaceutical, and cosmetic industries. This study compares hydrodynamic cavitation (HC) and conventio...

Advances and Outlook of Tea Polyphenol Chemistry: A Review.

Journal of agricultural and food chemistry
Tea is one of the most widely consumed beverages globally, whereas tea polyphenols are always receiving the most attention in scientific research. In past decades, the polyphenols, their derivatives, and oligomers and polymers which possess potential...