AIMC Topic: Plant Extracts

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Extract optimization and biological activities of Otidea onotica using Artificial Neural Network-Genetic Algorithm and response surface methodology techniques.

BMC biotechnology
In this study, the biological activities of Otidea onotica were investigated using two optimization methods, Response Surface Methodology (RSM) and Artificial Neural Network-Genetic Algorithm (ANN-GA). The extracts were tested for phenolic content, a...

Rapid evaluation of Curcuma origin and quality based on E-eye, flash GC e-nose, and FT-NIR combined with machine learning technologies.

Food chemistry
Curcuma, a key ingredient in curry and a popular health supplement, has been subject to adulteration and fraudulent origin labeling. In this study, E-eye, Flash GC e-nose, and FT-NIR, combined with machine learning and multivariate algorithms, were e...

Antioxidant activity of Mentha piperita phenolics on arsenic induced oxidative stress, biochemical alterations, and cyto-genotoxicity in fish, Channa punctatus.

Fish physiology and biochemistry
The study aims to investigate the synergistic antioxidant effects of the phenolics present in Mentha piperita (MP) against arsenic trioxide-induced oxidative stress, biochemical alteration, and cyto-genotoxicity in the fish, Channa punctatus. The phe...

Bioactivity of Juglans regia kernel extracts optimized using response surface method and artificial neural Network-Genetic algorithm integration.

Scientific reports
In this study, the biological activities of the extracts obtained under optimum extraction conditions of the kernel part of Juglans regia L. were determined. Two different methods, Response Surface Method (RSM) and Artificial Neural Network-Genetic A...

Optimization of enzyme-ultrasound assisted extraction from mulberries anthocyanins based on response surface methodology and deep neural networks and analysis of in vitro antioxidant activities.

Food chemistry
This study used Xinjiang native "medicinal and food dual-use" resource mulberries as raw material, and optimized the extraction process of mulberries anthocyanins by enzyme-ultrasound-assistance through the establishment of a response surface model (...

Differentiation of Citri Reticulatae Pericarpium varieties via HPLC fingerprinting of polysaccharides combined with machine learning.

Food chemistry
To accurately and reliably distinguish different varieties of Citri Reticulatae Pericarpium (CRP), we propose a novel classification strategy combining polysaccharide fingerprinting and machine learning (ML). First, extraction conditions are optimize...

Physalis Calyx seu Fructus relieves chicken intestinal damage to heat via improving the antioxidant ability.

Frontiers in immunology
Heat-stress-induced oxidative and inflammatory responses were important factors contributing to chicken intestinal damage. The purpose of this study was based on the antioxidant and anti-inflammatory activities of Physalis Calyx seu Fructus (Jin Deng...

Investigation of alpha-glucosidase inhibition activity of Artabotrys sumatranus leaf extract using metabolomics, machine learning and molecular docking analysis.

PloS one
One way to treat diabetes mellitus type II is by using α-glucosidase inhibitor, that will slow down the postprandial glucose intake. Metabolomics analysis of Artabotrys sumatranus leaf extract was used in this research to predict the active compounds...

LC-MS profiling and cytotoxic activity of Angiopteris helferiana against HepG2 cell line: Molecular insight to investigate anticancer agent.

PloS one
Liver cancer is one of the most prevalent malignant diseases in humans and the second leading cause of cancer-related mortality globally. Angiopteris helferiana was mentioned as a possible anticancer herb according to ethnomedicinal applications. How...

A hybrid artificial neural network and multi-objective genetic algorithm approach to optimize extraction conditions of Mentha longifolia and biological activities.

Scientific reports
In this work, artificial neural network coupled with multi-objective genetic algorithm (ANN-NSGA-II) has been used to develop a model and optimize the conditions for the extracting of the Mentha longifolia (L.) L. plant. Input parameters were extract...