AIMC Topic: Polymorphism, Single Nucleotide

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ASSOCIATION BETWEEN MURINE DOUBLE MINUTE 2 - T309G polymorphism and recurrence of hepatocellular carcinoma after surgical treatment.

Arquivos de gastroenterologia
BACKGROUND: Discovery and incorporation of biomarker panels to cancer studies enabled the understanding of genetic variation and its interference in carcinogenesis at molecular level. The potential association between single nucleotide polymorphism (...

Mining nutrigenetics patterns related to obesity: use of parallel multifactor dimensionality reduction.

International journal of bioinformatics research and applications
This paper aims to enlighten the complex etiology beneath obesity by analysing data from a large nutrigenetics study, in which nutritional and genetic factors associated with obesity were recorded for around two thousand individuals. In our previous ...

Discovery of phenotypic networks from genotypic association studies with application to obesity.

International journal of data mining and bioinformatics
Genome-wide Association Studies (GWAS) have resulted in many discovered risk variants for several obesity-related traits. However, before clinical relevance of these discoveries can be achieved, molecular or physiological mechanisms of these risk var...