AIMC Topic: Porosity

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A study of intracortical porosity's area fractions and aspect ratios using computer vision and pulse-coupled neural networks.

Medical & biological engineering & computing
Employing computer vision (CV) and optimized pulse-coupled neural networks (PCNN), this work automatically quantifies the geometrical attributes of intracortical bone porosity (namely lacunae and canaliculi (L-C), Haversian canals, and resorption cav...

Simultaneous determination of 11 phthalate esters in bottled beverages by graphene oxide coated hollow fiber membrane extraction coupled with supercritical fluid chromatography.

Analytica chimica acta
Phthalate esters (PAEs) are a group of serious environmental pollutants, which lead to carcinogenicity or tumorigenicity in human body. In this study, a rapid, sensitive and green method by graphene oxide coated hollow fiber membrane extraction (GO-H...

Graphene oxide-doping improves the biocompatibility and separation performance of polyethersulfone hollow fiber membranes for bioartificial kidney application.

Journal of colloid and interface science
HYPOTHESIS: Graphene oxide (GO)-doping in polyethersulfone hollow fiber membranes (PES HFMs) improves the biocompatibility and separation performance for bioartificial kidney (BAK) application.

Computational fluid dynamics study of viscous fingering in supercritical fluid chromatography.

Journal of chromatography. A
Axi-symmetric numerical simulations are carried out to study the dynamics of a plug introduced through a mixed-stream injection in supercritical fluid chromatographic columns. The computational fluid dynamics model developed in this work takes into a...

Computational intelligence models to predict porosity of tablets using minimum features.

Drug design, development and therapy
The effects of different formulations and manufacturing process conditions on the physical properties of a solid dosage form are of importance to the pharmaceutical industry. It is vital to have in-depth understanding of the material properties and g...

Controlled surface morphology and hydrophilicity of polycaprolactone toward human retinal pigment epithelium cells.

Materials science & engineering. C, Materials for biological applications
Applying scaffolds as a bed to enhance cell proliferation and even differentiation is one of the treatment of retina diseases such as age-related macular degeneration (AMD) which deteriorating photoreceptors and finally happening blindness. In this s...

Determination of the mechanical and physical properties of cartilage by coupling poroelastic-based finite element models of indentation with artificial neural networks.

Journal of biomechanics
One of the most widely used techniques to determine the mechanical properties of cartilage is based on indentation tests and interpretation of the obtained force-time or displacement-time data. In the current computational approaches, one needs to si...

Poroelastic Foams for Simple Fabrication of Complex Soft Robots.

Advanced materials (Deerfield Beach, Fla.)
Open-celled, elastomeric foams allow the simple design of fully 3D pneumatic soft machines using common forming techniques. This is demonstrated through the fabrication of simple actuators and an entirely soft, functional fluid pump formed in the sha...

A methodological evaluation and predictive in silico investigation into the multi-functionality of arginine in directly compressed tablets.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
The acceleration of solid dosage form product development can be facilitated by the inclusion of excipients that exhibit poly-/multi-functionality with reduction of the time invested in multiple excipient optimisations. Because active pharmaceutical ...

Machine learning predictions of drug release from isocyanate-derived aerogels.

Journal of materials chemistry. B
This work utilized machine learning (ML) algorithms to predict and validate the drug release kinetics of a short worm-like nanostructured isocyanate-derived aerogel: the first time ML has been employed to study the drug delivery properties of this i...