PURPOSE: A novel AI-based 3D analysis system was developed to automatically extract bone and cartilage from MRI data and provide average cartilage thickness. This study aimed to analyze the interscan measurement error of knee cartilage thickness in o...
Cellular senescence is an irreversible state of cell cycle arrest with a complex role in tissue repair, aging, and disease. However, inconsistencies in identifying cellular senescence have led to varying conclusions about their functional significanc...
In this study, we explore the potential of ten quantitative (radiofrequency-based) ultrasound parameters to assess the progressive loss of collagen and proteoglycans, mimicking an osteoarthritis condition in ex-vivo bovine cartilage samples. Most ana...
PURPOSE: Magnetic Resonance Imaging (MRI) based three-dimensional analysis of knee cartilage has evolved to become fully automatic. However, when implementing these measurements across multiple clinical centers, scanner variability becomes a critical...
The American journal of sports medicine
Jun 7, 2025
BACKGROUND: Multiple 2-dimensional magnetic resonance imaging (MRI) studies have indicated that the size of the labrum adjusts in response to altered joint loading. In patients with hip dysplasia, it tends to increase as a compensatory mechanism for ...
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Mar 20, 2025
Articular cartilage, essential for smooth joint movement, can sustain micrometer-scale microcracks in its collagen network from low-energy impacts previously considered non-injurious. These microcracks may propagate under cyclic loading, impairing ca...
The objective was to use convolutional neural networks (CNNs) for automatic segmentation of hip cartilage and labrum based on 3D MRI. In this retrospective single-center study, CNNs with a U-Net architecture were used to develop a fully automated seg...
Journal of magnetic resonance imaging : JMRI
Jan 10, 2025
Osteoarthritis (OA) is heterogeneous and involves structural changes in the whole joint, such as cartilage, meniscus/labrum, ligaments, and tendons, mainly with short T2 relaxation times. Detecting OA before the onset of irreversible changes is cruci...
Osteochondral interface consists of two tissues: the calcified cartilage (CC) containing chondrocytes, and subchondral bone (SCB) containing osteocytes that interact with each other. In this study, we propose a new method for the three-dimensional (3...
Vibrational spectroscopy methods such as mid-infrared (MIR), near-infrared (NIR), and Raman spectroscopies have been shown to have great potential for in vivo biomedical applications, such as arthroscopic evaluation of joint injuries and degeneration...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.