BACKGROUND: Knee cartilage injury (KCI) poses significant challenges in the early clinical diagnosis process, primarily due to its high incidence, the complexity of healing, and the limited sensitivity of initial imaging modalities.
OBJECTIVES: To develop a cascaded machine learning model based on MRI radiomics features from cartilage and subchondral bone to predict the incidence and progression of knee osteoarthritis (KOA), thereby addressing the need for early intervention in ...
OBJECTIVE: The 3-dimensional (3D) double echo steady state (DESS) magnetic resonance imaging sequence can image knee cartilage with high, isotropic resolution, particularly at high and ultra-high field strengths. Advanced undersampling techniques wit...
PURPOSE: A novel AI-based 3D analysis system was developed to automatically extract bone and cartilage from MRI data and provide average cartilage thickness. This study aimed to analyze the interscan measurement error of knee cartilage thickness in o...
Cellular senescence is an irreversible state of cell cycle arrest with a complex role in tissue repair, aging, and disease. However, inconsistencies in identifying cellular senescence have led to varying conclusions about their functional significanc...
In this study, we explore the potential of ten quantitative (radiofrequency-based) ultrasound parameters to assess the progressive loss of collagen and proteoglycans, mimicking an osteoarthritis condition in ex-vivo bovine cartilage samples. Most ana...
PURPOSE: Magnetic Resonance Imaging (MRI) based three-dimensional analysis of knee cartilage has evolved to become fully automatic. However, when implementing these measurements across multiple clinical centers, scanner variability becomes a critical...
The American journal of sports medicine
Jun 7, 2025
BACKGROUND: Multiple 2-dimensional magnetic resonance imaging (MRI) studies have indicated that the size of the labrum adjusts in response to altered joint loading. In patients with hip dysplasia, it tends to increase as a compensatory mechanism for ...
OBJECTIVES: To evaluate the performance of high-resolution deep learning-based hip MR imaging (CSAI) compared to standard-resolution compressed sense (CS) sequences using hip arthroscopy as standard of reference.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Mar 20, 2025
Articular cartilage, essential for smooth joint movement, can sustain micrometer-scale microcracks in its collagen network from low-energy impacts previously considered non-injurious. These microcracks may propagate under cyclic loading, impairing ca...
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