This study developed machine learning models to predict Aβ positivity in Alzheimer's disease by integrating early-phase F-Florbetaben PET and clinical data to improve diagnostic accuracy. Furthermore, the study explored machine learning models to pre...
AIM: This study aimed to assess and compare the performance of nomograms and machine learning (ML) techniques using preoperative biomarkers for predicting side-specific extraprostatic extension (EPE) in prostate cancer, which is linked to poor outcom...
BACKGROUND: Widely used in oncology PET, 2-deoxy-2- 18 F-FDG PET is more accessible and affordable than amyloid PET, which is a crucial tool to determine amyloid positivity in diagnosis of Alzheimer disease (AD). This study aimed to leverage deep lea...
BACKGROUND/PURPOSE: Multiple parametric imaging in positron emission tomography (PET) is challenging due to the noisy dynamic data and the complex mapping to kinetic parameters. Although methods like direct parametric reconstruction have been propose...
The recent approval of anti-amyloid pharmaceuticals for the treatment of Alzheimer's disease (AD) has created a pressing need for the ability to accurately identify optimal candidates for anti-amyloid therapy, specifically those with evidence for inc...
OBJECTIVE: PET image analysis provides tumor heterogeneity data related to neoadjuvant chemotherapy response (NACR) and metastatic risk in osteosarcoma. Ki-67 expression is used to predict metastasis. The accuracy of prediction models with image quan...
BACKGROUND: Since the approval of disease-modifying drugs for Alzheimer's disease, the demand for amyloid positron emission tomography (PET) scans, which are crucial for determining treatment eligibility, is expected to increase significantly. We thu...
Alzheimer's Disease (AD) as one of the most prevalent neurodegenerative disorders worldwide, characterized by significant memory and cognitive decline in its later stages, severely impacting daily lives. Consequently, early diagnosis and accurate ass...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Apr 14, 2025
BACKGROUND: The presence of a gap between adjacent detector blocks in Positron Emission Tomography (PET) scanners introduces a partial loss of projection data, which can degrade the image quality and quantitative accuracy of reconstructed PET images....
. Pixelated detectors with single-ended readout are routinely used by commercial positron emission tomography scanners owing to their good energy and timing resolution and optimized manufacturing, but they typically do not provide depth-of-interactio...
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