AIMC Topic: Antigens, Surface

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PSMA PET Evaluation with a Deep Learning Platform Compared with a Standard Image Viewer and Histopathology.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine Dec 3, 2025
Standardized prostate-specific membrane antigen (PSMA) PET/CT evaluation and reporting was introduced to aid interpretation, reproducibility, and communication. Artificial intelligence may enhance these efforts. This study aimed to evaluate the perfo...
Humans Retrospective Studies Positron Emission Tomography Computed Tomography Reproducibility of Results Prostatic Neoplasms Aged Male Middle Aged Deep Learning Image Processing, Computer-Assisted Antigens, Surface Gallium Radioisotopes Glutamate Carboxypeptidase II
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Prognostic Value of AI-Assisted Lesion Tracking on End-of-Treatment PSMA PET in mCRPC Patients Treated with Lu-PSMA: A Retrospective, Single-Center Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine Nov 3, 2025
This study aimed to explore the prognostic value of the artificial intelligence-assisted lesion tracking applied to prostate-specific membrane antigen (PSMA) PET in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with PS...
Humans Artificial Intelligence Prognosis Retrospective Studies Treatment Outcome Prostate-Specific Antigen Radiopharmaceuticals Positron-Emission Tomography Aged Aged, 80 and over Male Middle Aged Glutamate Carboxypeptidase II Lutetium Heterocyclic Compounds, 1-Ring Dipeptides Prostatic Neoplasms, Castration-Resistant Radioisotopes Antigens, Surface
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Machine learning-based transcriptomic analysis identifies NAMPT and SAT1 as potential biomarkers and therapeutic targets in ferroptosis-associated rheumatoid arthritis.

PloS one Sep 29, 2025
BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease with chronic presentation, involving symmetric joints and systemic involvement. Ferroptosis is iron-dependent programmed cell death through lipid peroxide accumulation, implicated in infl...
Databases, Genetic Ferroptosis Nicotinamide Phosphoribosyltransferase Antigens, Surface Machine Learning Cytokines Biomarkers Gene Expression Profiling Transcriptome Protein Interaction Maps Gene Regulatory Networks Humans Arthritis, Rheumatoid
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Treatment Response Evaluation in Prostate Cancer Using PSMA PET/CT.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine Jul 1, 2025
In recent years, there has been a headlong rush into the use of prostate-specific membrane antigen (PSMA)-targeted PET for the staging and restaging of men with prostate cancer (PC). To date, there have been regulatory approvals for PSMA PET for purp...
Positron Emission Tomography Computed Tomography Prostatic Neoplasms Antigens, Surface Glutamate Carboxypeptidase II Humans Male Treatment Outcome
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PSMA PET/CT for prostate cancer diagnosis: current applications and future directions.

Journal of cancer research and clinical oncology May 4, 2025
Prostate cancer (PCa) requires improved diagnostic strategies beyond conventional imaging. This review aimed to evaluate the role of prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) in diagnosing advan...
Prostatic Neoplasms Humans Antigens, Surface Male Glutamate Carboxypeptidase II Lymphatic Metastasis Positron Emission Tomography Computed Tomography
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The Value of Artificial Intelligence in Prostate-Specific Membrane Antigen Positron Emission Tomography: An Update.

Seminars in nuclear medicine Jan 31, 2025
This review aims to provide an up-to-date overview of the utility of artificial intelligence (AI) in evaluating prostate-specific membrane antigen (PSMA) positron emission tomography (PET) scans for prostate cancer (PCa). A literature review was cond...
Artificial Intelligence Male Image Processing, Computer-Assisted Prostatic Neoplasms Positron-Emission Tomography Humans Antigens, Surface Glutamate Carboxypeptidase II
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PSMA PET/CT based multimodal deep learning model for accurate prediction of pelvic lymph-node metastases in prostate cancer patients identified as candidates for extended pelvic lymph node dissection by preoperative nomograms.

European journal of nuclear medicine and molecular imaging Jan 27, 2025
PURPOSE: To develop and validate a prostate-specific membrane antigen (PSMA) PET/CT based multimodal deep learning model for predicting pathological lymph node invasion (LNI) in prostate cancer (PCa) patients identified as candidates for extended pel...
Prostatic Neoplasms Pelvis Preoperative Period Antigens, Surface Glutamate Carboxypeptidase II Nomograms Lymphatic Metastasis Lymph Node Excision Positron Emission Tomography Computed Tomography Aged Male Middle Aged Deep Learning Humans
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The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis.

Frontiers in immunology Jan 23, 2025
BACKGROUND: Severe Community-Acquired Pneumonia (SCAP) is a serious global health issue with high incidence and mortality rates. In recent years, the role of biomarkers such as Connective Tissue Growth Factor (CTGF) and Milk Fat Globule-Epidermal Gro...
Humans Machine Learning Prospective Studies Biomarkers Prognosis Female Aged Adult Antigens, Surface Milk Proteins Connective Tissue Growth Factor Male Middle Aged Nomograms Pneumonia
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Prediction of Lesion-Based Treatment Response after Two Cycles of Lu-177 Prostate Specific Membrane Antigen Treatment in Metastatic Castration-Resistant Prostate Cancer Using Machine Learning.

Urologia internationalis Sep 30, 2024
INTRODUCTION: Lutetium-177 (Lu-177) prostate-specific membrane antigen (PSMA) therapy is a radionuclide treatment that prolongs overall survival in metastatic castration-resistant prostate cancer (MCRPC). We aimed to predict lesion-based treatment re...
Antigens, Surface Gallium Radioisotopes Glutamate Carboxypeptidase II Machine Learning Lutetium Retrospective Studies Radiopharmaceuticals Humans Male Aged Neoplasm Metastasis Middle Aged Prostatic Neoplasms, Castration-Resistant Aged, 80 and over Treatment Outcome Radioisotopes Positron Emission Tomography Computed Tomography
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A Machine Learning Approach for Predicting Biochemical Outcome After PSMA-PET-Guided Salvage Radiotherapy in Recurrent Prostate Cancer After Radical Prostatectomy: Retrospective Study.

JMIR cancer Sep 20, 2024
BACKGROUND: Salvage radiation therapy (sRT) is often the sole curative option in patients with biochemical recurrence after radical prostatectomy. After sRT, we developed and validated a nomogram to predict freedom from biochemical failure.
Prostatectomy Antigens, Surface Glutamate Carboxypeptidase II Radiotherapy, Image-Guided Prostate-Specific Antigen Neoplasm Recurrence, Local Positron-Emission Tomography Salvage Therapy Male Humans Middle Aged Machine Learning Nomograms Retrospective Studies Prostatic Neoplasms Aged
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