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Principal Component Analysis

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Global gene network exploration based on explainable artificial intelligence approach.

PloS one
In recent years, personalized gene regulatory networks have received significant attention, and interpretation of the multilayer networks has been a critical issue for a comprehensive understanding of gene regulatory systems. Although several statist...

Concentration-Emission Matrix (CEM) Spectroscopy Combined with GA-SVM: An Analytical Method to Recognize Oil Species in Marine.

Molecules (Basel, Switzerland)
The establishment and development of a set of methods of oil accurate recognition in a different environment are of great significance to the effective management of oil spill pollution. In this work, the concentration-emission matrix (CEM) is formed...

COSMO-RS-Based Descriptors for the Machine Learning-Enabled Screening of Nucleotide Analogue Drugs against SARS-CoV-2.

The journal of physical chemistry letters
Chemical similarity-based approaches employed to repurpose or develop new treatments for emerging diseases, such as COVID-19, correlates molecular structure-based descriptors of drugs with those of a physiological counterpart or clinical phenotype. W...

Traffic Crash Severity Prediction-A Synergy by Hybrid Principal Component Analysis and Machine Learning Models.

International journal of environmental research and public health
The accurate prediction of road traffic crash (RTC) severity contributes to generating crucial information, which can be used to adopt appropriate measures to reduce the aftermath of crashes. This study aims to develop a hybrid system using principal...

Large-Scale Multi-omic Analysis of COVID-19 Severity.

Cell systems
We performed RNA-seq and high-resolution mass spectrometry on 128 blood samples from COVID-19-positive and COVID-19-negative patients with diverse disease severities and outcomes. Quantified transcripts, proteins, metabolites, and lipids were associa...

Study of morphological and textural features for classification of oral squamous cell carcinoma by traditional machine learning techniques.

Cancer reports (Hoboken, N.J.)
BACKGROUND: Oral squamous cell carcinoma (OSCC) is the most prevalent form of oral cancer. Very few researches have been carried out for the automatic diagnosis of OSCC using artificial intelligence techniques. Though biopsy is the ultimate test for ...

Classification and Quantification of Microplastics (<100 μm) Using a Focal Plane Array-Fourier Transform Infrared Imaging System and Machine Learning.

Analytical chemistry
Microplastics are defined as microscopic plastic particles in the range from few micrometers and up to 5 mm. These small particles are classified as primary microplastics when they are manufactured in this size range, whereas secondary microplastics ...

Machine Learning-Assisted Raman Spectroscopy for pH and Lactate Sensing in Body Fluids.

Analytical chemistry
This study presents the combination of Raman spectroscopy with machine learning algorithms as a prospective diagnostic tool capable of detecting and monitoring relevant variations of pH and lactate as recognized biomarkers of several pathologies. The...

Deep Spectral-Spatial Features of Near Infrared Hyperspectral Images for Pixel-Wise Classification of Food Products.

Sensors (Basel, Switzerland)
Hyperspectral imaging (HSI) emerges as a non-destructive and rapid analytical tool for assessing food quality, safety, and authenticity. This work aims to investigate the potential of combining the spectral and spatial features of HSI data with the a...

Machine learning utilising spectral derivative data improves cellular health classification through hyperspectral infra-red spectroscopy.

PloS one
The objective differentiation of facets of cellular metabolism is important for several clinical applications, including accurate definition of tumour boundaries and targeted wound debridement. To this end, spectral biomarkers to differentiate live a...