AIMC Topic: Proton Therapy

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A denoising method based on deep learning for proton radiograph using energy resolved dose function.

Physics in medicine and biology Jan 11, 2024
Proton radiograph has been broadly applied in proton radiotherapy which is affected by scattered protons which result in the lower spatial resolution of proton radiographs than that of x-ray images. Traditional image denoising method may lead to the ...
Protons Deep Learning Radiation, Ionizing Water Phantoms, Imaging Radiography Proton Therapy
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Deep learning-based synthetic dose-weighted LET map generation for intensity modulated proton therapy.

Physics in medicine and biology Jan 5, 2024
The advantage of proton therapy as compared to photon therapy stems from the Bragg peak effect, which allows protons to deposit most of their energy directly at the tumor while sparing healthy tissue. However, even with such benefits, proton therapy ...
Radiotherapy Planning, Computer-Assisted Protons Monte Carlo Method Linear Energy Transfer Deep Learning Proton Therapy Relative Biological Effectiveness
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Feasibility of Monte Carlo dropout-based uncertainty maps to evaluate deep learning-based synthetic CTs for adaptive proton therapy.

Medical physics Nov 13, 2023
BACKGROUND: Deep learning has shown promising results to generate MRI-based synthetic CTs and to enable accurate proton dose calculations on MRIs. For clinical implementation of synthetic CTs, quality assurance tools that verify their quality and rel...
Tomography, X-Ray Computed Reproducibility of Results Deep Learning Proton Therapy Feasibility Studies Image Processing, Computer-Assisted Radiotherapy Planning, Computer-Assisted Uncertainty Magnetic Resonance Imaging Radiotherapy Dosage Protons
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Technical note: Evaluation of deep learning based synthetic CTs clinical readiness for dose and NTCP driven head and neck adaptive proton therapy.

Medical physics Oct 13, 2023
BACKGROUND: Adaptive proton therapy workflows rely on accurate imaging throughout the treatment course. Our centre currently utilizes weekly repeat CTs (rCTs) for treatment monitoring and plan adaptations. However, deep learning-based methods have re...
Deglutition Disorders Proton Therapy Radiotherapy Dosage Cone-Beam Computed Tomography Radiotherapy, Intensity-Modulated Humans Xerostomia Head and Neck Neoplasms Deep Learning Radiotherapy Planning, Computer-Assisted
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Comparison and evaluation of different deep learning models of synthetic CT generation from CBCT for nasopharynx cancer adaptive proton therapy.

Medical physics Oct 6, 2023
BACKGROUND: Cone-beam computed tomography (CBCT) scanning is used for patient setup in image-guided radiotherapy. However, its inaccurate CT numbers limit its applicability in dose calculation and treatment planning.
Nasopharyngeal Neoplasms Proton Therapy Spiral Cone-Beam Computed Tomography Image Processing, Computer-Assisted Radiotherapy Planning, Computer-Assisted Radiotherapy Dosage Deep Learning Cone-Beam Computed Tomography Humans
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Multimodal imaging-based material mass density estimation for proton therapy using supervised deep learning.

The British journal of radiology Oct 3, 2023
OBJECTIVE: Mapping CT number to material property dominates the proton range uncertainty. This work aims to develop a physics-constrained deep learning-based multimodal imaging (PDMI) framework to integrate physics, deep learning, MRI, and advanced d...
Image Processing, Computer-Assisted Magnetic Resonance Imaging Obesity Tomography, X-Ray Computed Deep Learning Multimodal Imaging Proton Therapy Protons Humans Retrospective Studies
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Beam mask and sliding window-facilitated deep learning-based accurate and efficient dose prediction for pencil beam scanning proton therapy.

Medical physics Sep 25, 2023
BACKGROUND: Accurate and efficient dose calculation is essential for on-line adaptive planning in proton therapy. Deep learning (DL) has shown promising dose prediction results in photon therapy. However, there is a scarcity of DL-based dose predicti...
Radiotherapy Planning, Computer-Assisted Radiotherapy Dosage Radiotherapy, Intensity-Modulated Proton Therapy Protons Deep Learning Lung Neoplasms Prostatic Neoplasms Humans Male
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Deep learning proton beam range estimation model for quality assurance based on two-dimensional scintillated light distributions in simulations.

Medical physics Jul 30, 2023
BACKGROUND: Many studies have utilized optical camera systems with volumetric scintillators for quality assurances (QA) to estimate the proton beam range. However, previous analytically driven range estimation methods have the difficulty to derive th...
Computer Simulation Monte Carlo Method Deep Learning Proton Therapy Water Protons Radiotherapy Dosage
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Automated treatment planning for proton pencil beam scanning using deep learning dose prediction and dose-mimicking optimization.

Journal of applied clinical medical physics Jun 19, 2023
PURPOSE: The purpose of this study is to investigate the use of a deep learning architecture for automated treatment planning for proton pencil beam scanning (PBS).
Proton Therapy Protons Radiotherapy Dosage Humans Radiotherapy, Intensity-Modulated Retrospective Studies Deep Learning Organs at Risk Radiotherapy Planning, Computer-Assisted
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Deep learning-based protoacoustic signal denoising for proton range verification.

Biomedical physics & engineering express May 12, 2023
Proton therapy is a type of radiation therapy that can provide better dose distribution compared to photon therapy by delivering most of the energy at the end of range, which is called the Bragg peak (BP). The protoacoustic technique was developed to...
Radiotherapy Dosage Deep Learning Proton Therapy Radiotherapy Planning, Computer-Assisted Protons
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