AIMC Topic: Pseudomonas aeruginosa

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Performance and hypothetical clinical impact of an mNGS-based machine learning model for antimicrobial susceptibility prediction of five ESKAPEE bacteria.

Microbiology spectrum
UNLABELLED: Antimicrobial resistance is an escalating global health crisis, underscoring the urgent need for timely and targeted therapies to ensure effective clinical treatment. We developed a machine learning model based on metagenomic next-generat...

Measuring water pollution effects on antimicrobial resistance through explainable artificial intelligence.

Environmental pollution (Barking, Essex : 1987)
Antimicrobial resistance refers to the ability of pathogens to develop resistance to drugs designed to eliminate them, making the infections they cause more difficult to treat and increasing the likelihood of disease diffusion and mortality. As such,...

High-content imaging and deep learning-driven detection of infectious bacteria in wounds.

Bioprocess and biosystems engineering
Fast and accurate detection of infectious bacteria in wounds is crucial for effective clinical treatment. However, traditional methods take over 24 h to yield results, which is inadequate for urgent clinical needs. Here, we introduce a deep learning-...

Identification of Staphylococcus aureus, Enterococcus faecium, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii from Raman spectra by Artificial Intelligent Raman Detection and Identification System (AIRDIS) with machine learning.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
BACKGROUND: Rapid and accurate identification of bacteria is required in order to develop effective treatment strategies. Traditional culture-based methods are time-consuming, while MALDI-TOF MS is expensive. The Raman spectroscopy, due to its relati...

Antimicrobial efficacy of an experimental UV-C robot in controlled conditions and in a real hospital scenario.

The Journal of hospital infection
BACKGROUND: Among no-touch automated disinfection devices, ultraviolet-C (UV-C) radiation has been proven to be one of the most effective against a broad spectrum of micro-organisms causing healthcare-associated infections.

Antibiotic resistance in : mechanisms and emerging treatment.

Critical reviews in microbiology
, able to survive on the surfaces of medical devices, is a life-threatening pathogen that mainly leads to nosocomial infection especially in immunodeficient and cystic fibrosis (CF) patients. The antibiotic resistance in has become a world-concernin...

Application of artificial neural network for the mechano-bactericidal effect of bioinspired nanopatterned surfaces.

European biophysics journal : EBJ
This study aimed to calculate the effect of nanopatterns' peak sharpness, width, and spacing parameters on P. aeruginosa and S. aureus cell walls by artificial neural network and finite element analysis. Elastic and creep deformation models of bacter...

Predicting drug resistance using artificial intelligence and clinical MALDI-TOF mass spectra.

mSystems
Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) is widely used in clinical microbiology laboratories for bacterial identification but its use for detection of antimicrobial resistance (AMR) remains limited....

VacSol-ML(ESKAPE) Machine learning empowering vaccine antigen prediction for ESKAPE pathogens.

Vaccine
The ESKAPE family, comprising Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp., poses a significant global threat due to their heightened virulence and extensiv...