We present DeepDose, a deep learning framework for fast dose calculations in radiation therapy. Given a patient anatomy and linear-accelerator IMRT multi-leaf-collimator shape or segment, a novel set of physics-based inputs is calculated that encode ...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Apr 1, 2020
PURPOSE: This study aims to investigate the feasibility of using convolutional neural networks to predict an accurate and high resolution dose distribution from an approximated and low resolution input dose.
Journal of applied clinical medical physics
Mar 30, 2020
PURPOSE: The authors have previously shown the feasibility of using an artificial neural network (ANN) to eliminate the volume average effect (VAE) of scanning ionization chambers (ICs). The purpose of this work was to evaluate the method when applie...
OBJECTIVES: To assess the impact on image quality and dose reduction of a new deep learning image reconstruction (DLIR) algorithm compared with a hybrid iterative reconstruction (IR) algorithm.
Currently methods for predicting absorbed dose after administering a radiopharmaceutical are rather crude in daily clinical practice. Most importantly, individual tissue density distributions as well as local variations of the concentration of the ra...
AJR. American journal of roentgenology
Jan 22, 2020
The objective of this study was to compare image quality and clinically significant lesion detection on deep learning reconstruction (DLR) and iterative reconstruction (IR) images of submillisievert chest and abdominopelvic CT. Our prospective mult...
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Jan 10, 2020
Our purpose was to assess the performance of full-dose (FD) PET image synthesis in both image and sinogram space from low-dose (LD) PET images and sinograms without sacrificing diagnostic quality using deep learning techniques. Clinical brain PET/CT...
RATIONALE AND OBJECTIVES: To evaluate the performance of iterative reconstruction (IR) and filtered back projection (FBP) images in terms of low-contrast detectability at different radiation doses, IR levels, and slice thickness using the mathematica...
PURPOSE: We propose a novel domain-specific loss, which is a differentiable loss function based on the dose-volume histogram (DVH), and combine it with an adversarial loss for the training of deep neural networks. In this study, we trained a neural n...