AIMC Topic: Radiotherapy Planning, Computer-Assisted

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Deep learning architecture with shunted transformer and 3D deformable convolution for voxel-level dose prediction of head and neck tumors.

Physical and engineering sciences in medicine
Intensity-modulated radiation therapy (IMRT) has been widely used in treating head and neck tumors. However, due to the complex anatomical structures in the head and neck region, it is challenging for the plan optimizer to rapidly generate clinically...

Automated segmentation in pelvic radiotherapy: A comprehensive evaluation of ATLAS-, machine learning-, and deep learning-based models.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Artificial intelligence can standardize and automatize highly demanding procedures, such as manual segmentation, especially in an anatomical site as common as the pelvis. This study investigated four automated segmentation tools on computed tomograph...

Integrating Deep Learning-Based Dose Distribution Prediction with Bayesian Networks for Decision Support in Radiotherapy for Upper Gastrointestinal Cancer.

Cancer research and treatment
PURPOSE: Selecting the better techniques to harbor optimal motion management, either a stereotactic linear accelerator delivery using TrueBeam (TBX) or magnetic resonance-guided gated delivery using MRIdian (MRG), is time-consuming and costly. To add...

Clinical implementation and evaluation of deep learning-assisted automatic radiotherapy treatment planning for lung cancer.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: The purpose of the study is to investigate the clinical application of deep learning (DL)-assisted automatic radiotherapy planning for lung cancer.

Improving 3D dose prediction for breast radiotherapy using novel glowing masks and gradient-weighted loss functions.

Medical physics
BACKGROUND: The quality of treatment plans for breast cancer can vary greatly. This variation could be reduced by using dose prediction to automate treatment planning. Our work investigates novel methods for training deep-learning models that are cap...

Improving the performance of deep learning models in predicting and classifying gamma passing rates with discriminative features and a class balancing technique: a retrospective cohort study.

Radiation oncology (London, England)
BACKGROUND: The purpose of this study was to improve the deep learning (DL) model performance in predicting and classifying IMRT gamma passing rate (GPR) by using input features related to machine parameters and a class balancing technique.

Deep-learning-based segmentation using individual patient data on prostate cancer radiation therapy.

PloS one
PURPOSE: Organ-at-risk segmentation is essential in adaptive radiotherapy (ART). Learning-based automatic segmentation can reduce committed labor and accelerate the ART process. In this study, an auto-segmentation model was developed by employing ind...

Enhanced 3D dose prediction for hypofractionated SRS (gamma knife radiosurgery) in brain tumor using cascaded-deep-supervised convolutional neural network.

Physical and engineering sciences in medicine
Gamma Knife radiosurgery (GKRS) is a well-established technique in radiation therapy (RT) for treating small-size brain tumors. It administers highly concentrated doses during each treatment fraction, with even minor dose errors posing a significant ...

Efficient application of deep learning-based elective lymph node regions delineation for pelvic malignancies.

Medical physics
BACKGROUND: While there are established international consensuses on the delineation of pelvic lymph node regions (LNRs), significant inter- and intra-observer variabilities persist. Contouring these clinical target volumes for irradiation in pelvic ...

Deep learning-based voxel sampling for particle therapy treatment planning.

Physics in medicine and biology
Scanned particle therapy often requires complex treatment plans, robust optimization, as well as treatment adaptation. Plan optimization is especially complicated for heavy ions due to the variable relative biological effectiveness. We present a nove...