BACKGROUND: Cancer is a disease that involves abnormal cell growth and can invade or metastasize to other tissues. It is known that several factors are related to its initiation, proliferation, and invasiveness. Recently, it has been reported that lo...
Recent study shows that long noncoding RNAs (lncRNAs) are participating in diverse biological processes and complex diseases. However, at present the functions of lncRNAs are still rarely known. In this study, we propose a network-based computational...
Long non-coding RNAs (lncRNAs) have been demonstrated to be significant in numerous biological processes. Hypertension is a form of cardiovascular disease with at least one billion cases worldwide. The present study sought to compare the differential...
MOTIVATION: Long non-coding RNAs (lncRNAs), which are non-coding RNAs of length above 200 nucleotides, play important biological functions such as gene expression regulation. To fully reveal the functions of lncRNAs, a fundamental step is to annotate...
Accurate annotation of coding regions in RNAs is essential for understanding gene translation. We developed a deep neural network to directly predict and analyze translation initiation and termination sites from RNA sequences. Trained with human tran...
Predicting long non-coding RNA (lncRNA)-protein interactions is essential for understanding biological processes and discovering new therapeutic targets. In this study, we propose a novel model based on inter-view contrastive learning and miRNA fusio...
Long non-coding RNAs (lncRNAs) are closely associated with the regulation of gene expression, whose promoters play a crucial role in comprehensively understanding lncRNA regulatory mechanisms, functions and their roles in diseases. Due to limitations...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2025
The interactions between long noncoding RNA (lncRNA) and protein play crucial roles in various biological processes. Computational methods are essential for predicting lncRNA-protein interactions and deciphering their mechanisms. In this chapter, we ...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2025
Single-cell omics technologies have revolutionized the study of long non-coding RNAs (lncRNAs), offering unprecedented resolution in elucidating their expression dynamics, cell-type specificity, and associated gene regulatory networks (GRNs). Concurr...
Shanghai kou qiang yi xue = Shanghai journal of stomatology
Dec 1, 2024
PURPOSE: To identify potential biomarkers of salivary gland adenoid cystic carcinoma to further understand the potential pathogenesis of adenoid cystic carcinoma.