Supervised learning methods promise to improve integrated testing strategies (ITS), but must be adjusted to handle high dimensionality and dose-response data. ITS approaches are currently fueled by the increasing mechanistic understanding of adverse ...
The skin sensitization potential of chemicals has been determined with the use of the murine local lymph node assay (LLNA). However, in recent years public concern about animal welfare has led to a requirement for non-animal risk assessment systems f...
Atopic dermatitis (AD) is a common and complex skin disease that significantly affects the quality of life of patients. The latest advances in artificial intelligence (AI) technology have introduced new methods for diagnosing, treating, and managing ...
BACKGROUND: Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma, and early-stage MF is difficult to differentiate from erythematous inflammatory disease. With the exception of biopsy, noninvasive information such as a patient'...
BACKGROUNDReversal reactions (RRs) in leprosy are acute immune episodes marked by inflammation and bacterial clearance, offering a model to study the dynamics of host responses to Mycobacterium leprae. These episodes are often severe and difficult to...
BACKGROUND: Skin quality has a significant influence on aesthetic perception, yet its clinical evaluation remains subjective and inconsistent. Traditional assessments, such as visual grading and manual scoring, lack reproducibility and fail to captur...
BACKGROUND: Skin burns result from thermal or chemical damage to the skin, requiring timely and accurate assessment for effective treatment. Determining the degree of burns is crucial for appropriate clinical decisions, especially for interventions l...
Animal growth is driven by the collective actions of cells, which are reciprocally influenced in real-time by the animal's overall growth state. Whereas cell behavior and animal growth state are expected to be tightly coupled, it is not yet determine...
Breast reconstruction using tissue expanders is the primary treatment option following mastectomy. Although skin growth in response to chronic supra-physiological stretch is well-established, individual patient factors such as breast shape, volume, s...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.