AIMC Topic: Software

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Evaluation of computational techniques for predicting non-synonymous single nucleotide variants pathogenicity.

Genomics
The human genetic diseases associated with many factors, one of these factors is the non-synonymous Single Nucleotide Variants (nsSNVs) cause single amino acid change with another resulting in protein function change leading to disease. Many computat...

An On-Chip Trainable and the Clock-Less Spiking Neural Network With 1R Memristive Synapses.

IEEE transactions on biomedical circuits and systems
Spiking neural networks (SNNs) are being explored in an attempt to mimic brain's capability to learn and recognize at low power. Crossbar architecture with highly scalable resistive RAM or RRAM array serving as synaptic weights and neuronal drivers i...

A machine learning based approach to identify protected health information in Chinese clinical text.

International journal of medical informatics
BACKGROUND: With the increasing application of electronic health records (EHRs) in the world, protecting private information in clinical text has drawn extensive attention from healthcare providers to researchers. De-identification, the process of id...

Estimating the refractive index of oxygenated and deoxygenated hemoglobin using genetic algorithm - support vector regression model.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVES: The refractive index of hemoglobin plays important role in hematology due to its strong correlation with the pathophysiology of different diseases. Measurement of the real part of the refractive index remains a challenge du...

Consistent prediction of GO protein localization.

Scientific reports
The GO-Cellular Component (GO-CC) ontology provides a controlled vocabulary for the consistent description of the subcellular compartments or macromolecular complexes where proteins may act. Current machine learning-based methods used for the automat...

Querying archetype-based EHRs by search ontology-based XPath engineering.

Journal of biomedical semantics
BACKGROUND: Legacy data and new structured data can be stored in a standardized format as XML-based EHRs on XML databases. Querying documents on these databases is crucial for answering research questions. Instead of using free text searches, that le...

Neural network control of focal position during time-lapse microscopy of cells.

Scientific reports
Live-cell microscopy is quickly becoming an indispensable technique for studying the dynamics of cellular processes. Maintaining the specimen in focus during image acquisition is crucial for high-throughput applications, especially for long experimen...

RaptorX-Angle: real-value prediction of protein backbone dihedral angles through a hybrid method of clustering and deep learning.

BMC bioinformatics
BACKGROUND: Protein dihedral angles provide a detailed description of protein local conformation. Predicted dihedral angles can be used to narrow down the conformational space of the whole polypeptide chain significantly, thus aiding protein tertiary...

Convolutional neural network-based classification system design with compressed wireless sensor network images.

PloS one
With the introduction of various advanced deep learning algorithms, initiatives for image classification systems have transitioned over from traditional machine learning algorithms (e.g., SVM) to Convolutional Neural Networks (CNNs) using deep learni...