Methylated RNA m6A immunoprecipitation sequencing (m6A-Seq) is a powerful technique for investigating transcriptome-wide m6A modification. However, most of the existing m6A-Seq protocols rely on reference genomes, limiting their use in species lackin...
Health technology assessment (Winchester, England)
May 1, 2025
BACKGROUND: Lung cancer is one of the most common types of cancer and the leading cause of cancer death in the United Kingdom. Artificial intelligence-based software has been developed to reduce the number of missed or misdiagnosed lung nodules on co...
Clinical and experimental rheumatology
May 1, 2025
Artificial intelligence (AI) is rapidly transforming radiology, with over 200 CE-marked products in the EU and more than 750 AI-based devices authorised by the FDA in the US, mainly used for x-ray, CT, MRI, and ultrasound imaging. Despite regulatory ...
RNA torsion and pseudo-torsion angles are critical in determining the three-dimensional conformation of RNA molecules, which in turn governs their biological functions. However, current methods are limited by RNA's structural complexity as well as fl...
Protein science : a publication of the Protein Society
May 1, 2025
Deep learning methods have played an increasingly pivotal role in advancing side-chain packing and mutation effect prediction (ΔΔG) for protein complexes. Although these two tasks are inherently closely related, they are typically treated separately ...
Purpose To present and evaluate Dafne (deep anatomical federated network), a freely available decentralized, collaborative deep learning system for the semantic segmentation of radiologic images through federated incremental learning. Materials and M...
Machine learning (ML) is rapidly gaining traction in many areas of experimental molecular science for elucidating relationships and patterns in large or complex data sets. Historically, ML was largely the preserve of those with specialized training i...
INTRODUCTION: Wound care is an essential discipline in plastic surgery, especially as the prevalence of chronic wounds, such as pressure injuries, is increasing. The escalating volume of patient data and the numerous variables influencing wound outco...
Phylogenetic inference aims at reconstructing the tree describing the evolution of a set of sequences descending from a common ancestor. The high computational cost of state-of-the-art maximum likelihood and Bayesian inference methods limits their us...
OBJECTIVES: Artificial intelligence (AI) software including Brainomix "e-CTA" which detect large vessel occlusions (LVO) have clinical potential. We hypothesized that in real world use where prevalence is low, its clinical utility may be overstated.
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