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Finding Relevant Retrosynthetic Disconnections for Stereocontrolled Reactions.

Journal of chemical information and modeling
Machine learning-driven computer-aided synthesis planning (CASP) tools have become important tools for idea generation in the design of complex molecule synthesis but do not adequately address the stereochemical features of the target compounds. A no...

Perceptions and detection of AI use in manuscript preparation for academic journals.

PloS one
The rapid advances in Generative AI tools have produced both excitement and worry about how AI will impact academic writing. However, little is known about what norms are emerging around AI use in manuscript preparation or how these norms might be en...

Geographical targeting of active case finding for tuberculosis in Pakistan using hotspots identified by artificial intelligence software (SPOT-TB): study protocol for a pragmatic stepped wedge cluster randomised control trial.

BMJ open respiratory research
INTRODUCTION: Pakistan has significantly strengthened its capacity for active case finding (ACF) for tuberculosis (TB) that is being implemented at scale in the country. However, yields of ACF have been lower than expected, raising concerns on its ef...

INDELpred: Improving the prediction and interpretation of indel pathogenicity within the clinical genome.

HGG advances
Small insertions and deletions (indels) are critical yet challenging genetic variations with significant clinical implications. However, the identification of pathogenic indels from neutral variants in clinical contexts remains an understudied proble...

AI-assisted Segmentation Tool for Brain Tumor MR Image Analysis.

Journal of imaging informatics in medicine
TumorPrism3D software was developed to segment brain tumors with a straightforward and user-friendly graphical interface applied to two- and three-dimensional brain magnetic resonance (MR) images. The MR images of 185 patients (103 males, 82 females)...

Knowledge graph revision in the context of unknown knowledge.

PloS one
The role of knowledge graph encompasses the representation, organization, retrieval, reasoning, and application of knowledge, providing a rich and robust cognitive foundation for artificial intelligence systems and applications. When we learn new thi...

Hitac: a hierarchical taxonomic classifier for fungal ITS sequences compatible with QIIME2.

BMC bioinformatics
BACKGROUND: Fungi play a key role in several important ecological functions, ranging from organic matter decomposition to symbiotic associations with plants. Moreover, fungi naturally inhabit the human body and can be beneficial when administered as ...

Predicting glycan structure from tandem mass spectrometry via deep learning.

Nature methods
Glycans constitute the most complicated post-translational modification, modulating protein activity in health and disease. However, structural annotation from tandem mass spectrometry (MS/MS) data is a bottleneck in glycomics, preventing high-throug...

Virtual resonance: analyzing IPA usage intensity under COVID-19's isolating canopy.

Scientific reports
The widespread adoption of smartphones coupled with advancements in artificial intelligence has significantly propelled the use of intelligent personal assistants (IPAs). These digital assistants have become indispensable for many users, particularly...