BACKGROUND: For many years, clinicians have been seeking for objective pain assessment solutions via neuroimaging techniques, focusing on the brain to detect human pain. Unfortunately, most of those techniques are not applicable in the clinical envir...
International journal of pharmaceutics
Jun 26, 2019
The aim of this work was to develop a PAT platform consisting of four complementary instruments for the characterization of electrospun amorphous solid dispersions with meloxicam. The investigated methods, namely NIR spectroscopy, Raman spectroscopy,...
International journal of pharmaceutics
Jun 25, 2019
This work proposes the application of artificial neural networks (ANN) to non-destructively predict the in vitro dissolution of pharmaceutical tablets from Process Analytical Technology (PAT) data. An extended release tablet formulation was studied, ...
This paper proposes a sensitive, sample preparation-free, rapid, and low-cost method for the detection of the B-rapidly accelerated fibrosarcoma (BRAF) gene mutation involving a substitution of valine to glutamic acid at codon 600 (V600E) in colorect...
In the analysis of functional Near-Infrared Spectroscopy (fNIRS) signals from real-world scenarios, artifact rejection is essential. However, currently there exists no gold-standard. Although a plenitude of methodological approaches implicitly assume...
Thermal Imaging (Infrared-Imaging-IRI) is a promising new technique for psychophysiological research and application. Unlike traditional physiological measures (like skin conductance and heart rate), it is uniquely contact-free, substantially enhanci...
Different multivariate data analysis methods were investigated and compared to optimize rapid and non-destructive quantitative detection of beef adulteration with spoiled beef based on visible near-infrared hyperspectral imaging. Four multivariate st...
Computer assisted surgery (Abingdon, England)
Jan 28, 2019
Near infrared spectroscopy is the promising and noninvasive technique that can be used to detect the brain functional activation by monitoring the concentration alternations in the haemodynamic concentration. The acquired NIRS signals are commonly co...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Dec 29, 2018
The reliability and validity of Vis-NIR hyperspectral imaging were investigated for the determination of heavy metal content in tomato leaves under different cadmium stress. Besides, a method involving wavelet transform and least square support vecto...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Oct 15, 2018
Spectroscopy is a powerful non-destructive quantization tool. In this paper, the technology is used to predict the nitrogen content of Masson pine seedling leaves. Masson pine is widely planted in China, and its nitrogen content is an important index...
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