Journal of molecular graphics & modelling
Nov 1, 2025
A kind of covalent modification known as post-translational modification (PTM) happens following the biosynthesis process, which is important in cell biology research. A reversible PTM called Lysine phosphoglycerylation alters glycolytic enzyme activ...
The mutagenicity of chemical compounds is a key consideration in toxicology, drug development, and environmental safety. Traditional methods such as the Ames test, while reliable, are time-intensive and costly. With advances in imaging and machine le...
Clinical chemistry and laboratory medicine
Sep 25, 2025
OBJECTIVES: This study aimed to develop and validate a machine learning (ML) model utilizing cerebrospinal fluid (CSF) body fluid parameters from hematology analyzers to screen for malignant cells.
Clinical chemistry and laboratory medicine
Sep 25, 2025
OBJECTIVES: Machine learning (ML) models, using laboratory data, support early sepsis prediction. However, analytical bias in laboratory measurements can compromise their performance and validity in real-world settings. We aimed to evaluate how analy...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Sep 5, 2025
The non-invasive real-time analysis of the composition of alternative, plant-based protein sources is important to control high moisture extrusion processes and ensure the quality and texture of the final extrudates used in the elaboration of meat an...
The American journal of tropical medicine and hygiene
Sep 3, 2025
Dengue with warning signs (DWS) and severe dengue are significant public health concerns in tropical and subtropical regions globally. Accurate and timely differentiation between these clinical forms of dengue, although crucial, is often complex. In ...
Long-duration space missions will challenge astronauts' adaptive capacities. Interoception and heart rate variability (HRV), reflecting parasympathetic activity, are increasingly recognized as predictors of adaptation and health. This study investiga...
PURPOSE: Music perception is a fundamental human experience, integral to cognitive and emotional processing, making it a crucial area for neuroscientific investigation. This study examined the neural dynamics underlying music perception and identifie...
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Sep 1, 2025
BACKGROUND: Chemotherapy-induced adverse drug reactions (ADRs) are common in patients with colorectal cancer. We developed four machine learning models to predict chemotherapy-induced ADRs and assessed the performance. These models leverage high-dime...
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