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Survival Analysis

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Defining Massive Transfusion in Civilian Pediatric Trauma With Traumatic Brain Injury.

The Journal of surgical research
The purpose of this study was to identify an optimal definition of massive transfusion in civilian pediatric trauma with severe traumatic brain injury (TBI) METHODS: Severely injured children (age ≤18 y) with severe TBI in the Trauma Quality Improvem...

Disparities in the Treatment and Outcome of Stage I Non-Small-Cell Lung Cancer in the 21st Century.

Clinical lung cancer
BACKGROUND: African American (AA) individuals are less likely to receive treatment and more likely to die from cancer compared with Caucasian (C) individuals. Recent advancements in surgery and radiation have improved outcomes in early stage non-smal...

Stage-Specific Survivability Prediction Models across Different Cancer Types.

AMIA ... Annual Symposium proceedings. AMIA Symposium
For all cancer types, survivability rates vary widely across different stages of cancer. But survivability prediction models built in past were trained using examples of all stages together and were also evaluated on all stages together. In this work...

Breast cancer data analysis for survivability studies and prediction.

Computer methods and programs in biomedicine
BACKGROUND: Breast cancer is the most common cancer affecting females worldwide. Breast cancer survivability prediction is challenging and a complex research task. Existing approaches engage statistical methods or supervised machine learning to asses...

Characterizing Autoimmune Disease-associated Diffuse Large B-cell Lymphoma in a SEER-Medicare Cohort.

Clinical lymphoma, myeloma & leukemia
BACKGROUND: Severe immune dysregulation such as seen in autoimmune (AI) disease is known to act as a significant risk factor for diffuse large B-cell lymphoma (DLBCL). However, little is known about the demographics or clinical outcomes of DLBCL that...

Prenatal Stress Exposure Generates Higher Early Survival and Smaller Size without Impacting Developmental Rate in a Pacific Salmon.

Journal of experimental zoology. Part A, Ecological genetics and physiology
Prenatal exposure to elevated glucocorticoids can act as a signal of environmental stress, resulting in modifications to offspring phenotype. While "negative" phenotypic effects (i.e., smaller size, slower growth) are often reported, recent research ...

Impact of chromogranin A, differentiation, and mitoses in nonfunctional pancreatic neuroendocrine tumors ≤ 2 cm.

The Journal of surgical research
BACKGROUND: Small pancreatic neuroendocrine tumors (PNETs) are a unique subset of pancreatic neoplasms. Chromogranin A (CgA) levels, mitotic rate, and histologic differentiation are often used to characterize PNET behavior. This study evaluates the i...