AIMC Topic: Synchrotrons

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Micro-morphological feature visualization, auto-classification, and evolution quantitative analysis of tumors by using SR-PCT.

Cancer medicine
Tissue micro-morphological abnormalities and interrelated quantitative data can provide immediate evidences for tumorigenesis and metastasis in microenvironment. However, the multiscale three-dimensional nondestructive pathological visualization, mea...

Flexible Learning-Free Segmentation and Reconstruction of Neural Volumes.

Scientific reports
Imaging is a dominant strategy for data collection in neuroscience, yielding stacks of images that often scale to gigabytes of data for a single experiment. Machine learning algorithms from computer vision can serve as a pair of virtual eyes that tir...

BioSAXS Sample Changer: a robotic sample changer for rapid and reliable high-throughput X-ray solution scattering experiments.

Acta crystallographica. Section D, Biological crystallography
Small-angle X-ray scattering (SAXS) of macromolecules in solution is in increasing demand by an ever more diverse research community, both academic and industrial. To better serve user needs, and to allow automated and high-throughput operation, a sa...

A Multimodal Transfer Learning Approach for Histopathology and SR-microCT Low-Data Regimes Image Segmentation.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Osteocyte-lacunar bone structures are a discerning marker for bone pathophysiology, given their geometric alterations observed during aging and diseases. Deep Learning (DL) image analysis has showcased the potential to comprehend bone health associat...

Pre- and Post-publication Verification for Reproducible Data Mining in Macromolecular Crystallography.

Methods in molecular biology (Clifton, N.J.)
Like an article narrative is deemed by an editor and referees to be worthy of being a version of record on acceptance as a publication, so must the underpinning data also be scrutinized before passing it as a version of record. Indeed without the und...

The combination of artificial neural networks and synchrotron radiation-based infrared micro-spectroscopy for a study on the protein composition of human glial tumors.

The Analyst
Protein-related changes associated with the development of human brain gliomas are of increasing interest in modern neuro-oncology. It is due to the fact that they might make some of these tumors highly aggressive and difficult to treat. This paper p...