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Synthetic Biology

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[Intelligent design of nucleic acid elements in biomanufacturing].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Nucleic acid elements are essential functional sequences that play critical roles in regulating gene expression, optimizing pathways, and enabling gene editing to enhance the production of target products in biomanufacturing. Therefore, the design an...

[Artificial intelligence-assisted design, mining, and modification of CRISPR-Cas systems].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
With the rapid advancement of synthetic biology, CRISPR-Cas systems have emerged as a powerful tool for gene editing, demonstrating significant potential in various fields, including medicine, agriculture, and industrial biotechnology. This review co...

[Databases, knowledge bases, and large models for biomanufacturing].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Biomanufacturing is an advanced manufacturing method that integrates biology, chemistry, and engineering. It utilizes renewable biomass and biological organisms as production media to scale up the production of target products through fermentation. C...

Engineering the future of medicine: Natural products, synthetic biology and artificial intelligence for next-generation therapeutics.

Clinical and translational medicine
The eXchange Unit between Thiolation domains approach and artificial intelligence (AI)-driven tools like Synthetic Intelligence are transforming nonribosomal peptide synthetase and polyketide synthase engineering, enabling the creation of novel bioac...

[Design and practice of integrating artificial intelligence into the teaching of "Synthetic Biology" under the background of discipline crossing].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
In recent years, artificial intelligence has been employed to empower synthetic biology, demonstrating great potential in the simulation and prediction of protein structures as well as the design and optimization of regulatory elements and metabolic ...

Virtual Labs and Designer Bugs - Generative AI, Synthetic Biology and National Security.

Journal of law and medicine
AI technologies can pose a major national security concern. AI programs could be used to develop chemical and biological agents which circumvent existing protective measures or medical treatments, or to design pathogens with capabilities they do not ...

Mechanistic Model-Driven Biodesign in Mammalian Synthetic Biology.

Methods in molecular biology (Clifton, N.J.)
Mathematical modeling plays a vital role in mammalian synthetic biology by providing a framework to design and optimize design circuits and engineered bioprocesses, predict their behavior, and guide experimental design. Here, we review recent models ...

Explorative Synthetic Biology in AI: Criteria of Relevance and a Taxonomy for Synthetic Models of Living and Cognitive Processes.

Artificial life
This article tackles the topic of the special issue "Biology in AI: New Frontiers in Hardware, Software and Wetware Modeling of Cognition" in two ways. It addresses the problem of the relevance of hardware, software, and wetware models for the scient...

Synthetic Biology Meets Machine Learning.

Methods in molecular biology (Clifton, N.J.)
This chapter outlines the myriad applications of machine learning (ML) in synthetic biology, specifically in engineering cell and protein activity, and metabolic pathways. Though by no means comprehensive, the chapter highlights several prominent com...

[Opportunities and challenges for fermentation optimization and scale-up technology in the artificial intelligence era].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Artificial intelligence (AI) technology is booming up a new industrial revolution, and its successful application is rapidly spreading from the information industry to many other fields. The traditional fermentation industry also faces more opportuni...