AIMC Topic: Terahertz Spectroscopy

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Rapid diagnosis of TERT promoter mutation using Terahertz absorption spectroscopy in glioblastoma.

Scientific reports
Glioblastoma (GBM) is a highly aggressive brain tumor with poor outcomes and limited treatment options. The telomerase reverse transcriptase (TERT) promoter mutation, one of the key biomarkers in GBM, is linked to tumor progression and prognosis. Thi...

A predictive model for MGMT promoter methylation status in glioblastoma based on terahertz spectral data.

Analytical biochemistry
O-methylguanine-DNA methyltransferase (MGMT) promoter methylation is a crucial biomarker in glioblastoma (GBM) that influences response to temozolomide. Traditional detection methods, such as gene sequencing, are time-consuming and limited to postope...

Design and Performance Evaluation of Machine Learning-Based Terahertz Metasurface Chemical Sensor.

IEEE transactions on nanobioscience
This paper presents a terahertz metasurface based sensor design incorporating graphene and other plasmonic materials for highly sensitive detection of different chemicals. The proposed sensor employs the combination of multiple resonator designs - in...

Terahertz molecular vibrational sensing using 3D printed anapole meta-biosensor.

Biosensors & bioelectronics
Terahertz (THz) fingerprint sensing utilizes the absorption of fingerprints generated by the unique vibrational characteristics of molecules to achieve substance-specific identification. By taking full advance of the anapole mode induced-biosensor co...

Identifying plastic materials in post-consumer food containers and packaging waste using terahertz spectroscopy and machine learning.

Waste management (New York, N.Y.)
Accurate identification of plastic materials from post-consumer food container and packaging waste is crucial for enhancing the purity and added value of recycled materials, thereby promoting recycling and addressing the issue of plastic pollution. H...

Discrimination of wheat gluten quality utilizing terahertz time-domain spectroscopy (THz-TDS).

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Wheat is an important food crop in the world, and wheat gluten quality is one of the important standards for judging the use of wheat. In this study, a combination of chemometric and machine learning methods based on THz-TDS were used to identify thr...

Roller compaction: Measuring ribbon porosity by terahertz spectroscopy and machine learning.

International journal of pharmaceutics
Roller compaction is a crucial unit operation in pharmaceutical manufacturing, with its ribbon porosity widely recognised as a critical quality attribute. Terahertz spectroscopy has emerged as a fast and non-destructive technique to measure porosity ...

An intelligent sensing platform for detecting and identifying biochemical substances based on terahertz spectra.

Talanta
This paper presents the development of an intelligent sensing platform dedicated to accurately identifying terahertz (THz) spectra obtained from various biochemical substances. The platform currently has two distinct identification modes, which focus...

Identification of Panax notoginseng origin using terahertz precision spectroscopy and neural network algorithm.

Talanta
Panax notoginseng (P. notoginseng), a Chinese herb containing various saponins, benefits immune system in medicines development, which from Wenshan (authentic cultivation) is often counterfeited by others for large demand and limited supply. Here, we...

Deep-Learning Terahertz Single-Cell Metabolic Viability Study.

ACS nano
Cell viability assessment is critical, yet existing assessments are not accurate enough. We report a cell viability evaluation method based on the metabolic ability of a single cell. Without culture medium, we measured the absorption of cells to tera...