AIMC Topic: Vascular Endothelial Growth Factor A

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Suitability of machine learning for atrophy and fibrosis development in neovascular age-related macular degeneration.

Acta ophthalmologica Dec 22, 2023
PURPOSE: To assess the suitability of machine learning (ML) techniques in predicting the development of fibrosis and atrophy in patients with neovascular age-related macular degeneration (nAMD), receiving anti-VEGF treatment over a 36-month period.
Humans Machine Learning Ranibizumab Wet Macular Degeneration Atrophy Visual Acuity Tomography, Optical Coherence Fundus Oculi Intravitreal Injections Aged, 80 and over Fluorescein Angiography Male Vascular Endothelial Growth Factor A Angiogenesis Inhibitors Fibrosis Follow-Up Studies Retrospective Studies Female Aged
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Preliminary analysis of predicting the first recurrence in patients with neovascular age-related macular degeneration using deep learning.

BMC ophthalmology Dec 7, 2023
BACKGROUND: To predict, using deep learning, the first recurrence in patients with neovascular age-related macular degeneration (nAMD) after three monthly loading injections of intravitreal anti-vascular endothelial growth factor (anti-VEGF).
Humans Intravitreal Injections Deep Learning Ranibizumab Angiogenesis Inhibitors Retina Wet Macular Degeneration Vascular Endothelial Growth Factor A Subretinal Fluid Tomography, Optical Coherence Macular Degeneration
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Predicting Visual Acuity Responses to Anti-VEGF Treatment in the Comparison of Age-related Macular Degeneration Treatments Trials Using Machine Learning.

Ophthalmology. Retina Nov 24, 2023
PURPOSE: To evaluate multiple machine learning (ML) models for predicting 2-year visual acuity (VA) responses to anti-vascular endothelial growth factor (anti-VEGF) treatment in the Comparison of Age-related Macular Degeneration (AMD) Treatments Tria...
Treatment Outcome Follow-Up Studies Visual Acuity Tomography, Optical Coherence Male ROC Curve Angiogenesis Inhibitors Wet Macular Degeneration Bevacizumab Vascular Endothelial Growth Factor A Intravitreal Injections Ranibizumab Humans Aged Aged, 80 and over Machine Learning Female
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Performance of retinal fluid monitoring in OCT imaging by automated deep learning versus human expert grading in neovascular AMD.

Eye (London, England) Jun 13, 2023
PURPOSE: To evaluate the reliability of automated fluid detection in identifying retinal fluid activity in OCT scans of patients treated with anti-VEGF therapy for neovascular age-related macular degeneration by correlating human expert and automated...
Wet Macular Degeneration Subretinal Fluid Tomography, Optical Coherence Vascular Endothelial Growth Factor A Intravitreal Injections Humans Deep Learning Reproducibility of Results Angiogenesis Inhibitors Visual Acuity
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Interpretable attention-based deep learning ensemble for personalized ovarian cancer treatment without manual annotations.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society Apr 12, 2023
Inhibition of pathological angiogenesis has become one of the first FDA approved targeted therapies widely tested in anti-cancer treatment, i.e. VEGF-targeting monoclonal antibody bevacizumab, in combination with chemotherapy for frontline and mainte...
Ovarian Neoplasms Vascular Endothelial Growth Factor A Pyruvate Kinase Deep Learning Humans Bevacizumab Antibodies, Monoclonal, Humanized Female Angiopoietin-2
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KFWC: A Knowledge-Driven Deep Learning Model for Fine-grained Classification of Wet-AMD.

Computer methods and programs in biomedicine Dec 15, 2022
BACKGROUND AND OBJECTIVES: Automated diagnosis using deep neural networks can help ophthalmologists detect the blinding eye disease wet Age-related Macular Degeneration (AMD). Wet-AMD has two similar subtypes, Neovascular AMD and Polypoidal Choroidal...
Humans Deep Learning Angiogenesis Inhibitors Fundus Oculi Vascular Endothelial Growth Factor A Fluorescein Angiography Visual Acuity Wet Macular Degeneration Tomography, Optical Coherence Polypoidal Choroidal Vasculopathy
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Establishing the Controlled Delivery of VEGF Using a Hydrogel Loaded Soft Robotic Drug Delivery System With the Aim to Prevascularise Implant Site for Islet Transplantation: Erratum.

Transplantation Nov 22, 2022
Robotics Vascular Endothelial Growth Factor A Hydrogels Drug Delivery Systems Islets of Langerhans Transplantation
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Correlation of vascular and fluid-related parameters in neovascular age-related macular degeneration using deep learning.

Acta ophthalmologica Aug 1, 2022
PURPOSE: To identify correlations between the vascular characteristics of macular neovascularization (MNV) obtained by optical coherence tomography angiography (OCTA) and distinct retinal fluid volumes in neovascular age-related macular degeneration ...
Humans Fluorescein Angiography Wet Macular Degeneration Tomography, Optical Coherence Prospective Studies Vascular Endothelial Growth Factor A Deep Learning Macular Degeneration Angiogenesis Inhibitors Intravitreal Injections
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Therapeutic response in the HAWK and HARRIER trials using deep learning in retinal fluid volume and compartment analysis.

Eye (London, England) May 6, 2022
OBJECTIVES: To assess the therapeutic response to brolucizumab and aflibercept by deep learning/OCT-based analysis of macular fluid volumes in neovascular age-related macular degeneration.
Wet Macular Degeneration Subretinal Fluid Retinal Detachment Vascular Endothelial Growth Factor A Intravitreal Injections Angiogenesis Inhibitors Ranibizumab Tomography, Optical Coherence Humans Deep Learning
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Clinically applicable deep learning-based decision aids for treatment of neovascular AMD.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Jan 22, 2022
PURPOSE: Anti-vascular endothelial growth factor (Anti-VEGF) therapy is currently seen as the standard for treatment of neovascular AMD (nAMD). However, while treatments are highly effective, decisions for initial treatment and retreatment are often ...
Tomography, Optical Coherence Deep Learning Vascular Endothelial Growth Factor A Humans Wet Macular Degeneration Angiogenesis Inhibitors Artificial Intelligence Visual Acuity Decision Support Techniques
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