AIMC Topic: Angiopoietin-2

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Inflammatory, fibrotic and endothelial biomarker profiles in COVID-19 patients during and following hospitalization.

Scientific reports Jul 10, 2025
Survivors of severe COVID-19 often suffer from long-term respiratory issues, but the molecular drivers of this damage remain unclear. This study explored the dynamics of inflammatory, fibrotic, and endothelial biomarkers in hospitalized COVID-19 pati...
Humans COVID-19 Inflammation Matrix Metalloproteinase 2 Middle Aged Respiratory Function Tests Angiopoietin-2 Fibrosis Aged Female Hyaluronic Acid Hospitalization SARS-CoV-2 Male Adult Biomarkers
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Machine Learning-Based Pathomics Model Predicts Angiopoietin-2 Expression and Prognosis in Hepatocellular Carcinoma.

The American journal of pathology Dec 31, 2024
Angiopoietin-2 (ANGPT2) shows promise as prognostic marker and therapeutic target in hepatocellular carcinoma (HCC). However, assessing ANGPT2 expression and prognostic potential using histopathology images viewed with naked eye is challenging. Herei...
Middle Aged Liver Neoplasms Male Angiopoietin-2 Carcinoma, Hepatocellular Female Prognosis Biomarkers, Tumor Aged Humans Machine Learning
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Interpretable attention-based deep learning ensemble for personalized ovarian cancer treatment without manual annotations.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society Apr 12, 2023
Inhibition of pathological angiogenesis has become one of the first FDA approved targeted therapies widely tested in anti-cancer treatment, i.e. VEGF-targeting monoclonal antibody bevacizumab, in combination with chemotherapy for frontline and mainte...
Angiopoietin-2 Humans Vascular Endothelial Growth Factor A Deep Learning Ovarian Neoplasms Antibodies, Monoclonal, Humanized Bevacizumab Pyruvate Kinase Female
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Hormone Receptor-Dependent Correlations Between Angiopoietins and VEGF-C in Primary Breast Cancer: Insights Into Lymphangiogenic Biomarkers.

Cancer reports (Hoboken, N.J.) May 1, 2025
BACKGROUND: Biomarkers of angiogenesis and lymphangiogenesis have been explored in cancer prognostic models; however, their potential role in assessing local tumor invasiveness remains poorly understood.
Middle Aged Angiopoietin-2 Aged Prognosis Lymphatic Metastasis Receptor, ErbB-2 Receptor, TIE-2 Female Receptors, Estrogen Biomarkers, Tumor Neovascularization, Pathologic Humans Iran Vascular Endothelial Growth Factor C Angiopoietin-1 Lymphangiogenesis Adult Receptors, Progesterone Breast Neoplasms
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