AIMC Topic: Angiopoietin-2

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Machine Learning-Based Pathomics Model Predicts Angiopoietin-2 Expression and Prognosis in Hepatocellular Carcinoma.

The American journal of pathology Dec 31, 2024
Angiopoietin-2 (ANGPT2) shows promise as prognostic marker and therapeutic target in hepatocellular carcinoma (HCC). However, assessing ANGPT2 expression and prognostic potential using histopathology images viewed with naked eye is challenging. Herei...
Humans Machine Learning Prognosis Female Aged Biomarkers, Tumor Male Middle Aged Liver Neoplasms Carcinoma, Hepatocellular Angiopoietin-2
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Interpretable attention-based deep learning ensemble for personalized ovarian cancer treatment without manual annotations.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society Apr 12, 2023
Inhibition of pathological angiogenesis has become one of the first FDA approved targeted therapies widely tested in anti-cancer treatment, i.e. VEGF-targeting monoclonal antibody bevacizumab, in combination with chemotherapy for frontline and mainte...
Humans Female Deep Learning Antibodies, Monoclonal, Humanized Ovarian Neoplasms Vascular Endothelial Growth Factor A Pyruvate Kinase Bevacizumab Angiopoietin-2
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Hormone Receptor-Dependent Correlations Between Angiopoietins and VEGF-C in Primary Breast Cancer: Insights Into Lymphangiogenic Biomarkers.

Cancer reports (Hoboken, N.J.) May 1, 2025
BACKGROUND: Biomarkers of angiogenesis and lymphangiogenesis have been explored in cancer prognostic models; however, their potential role in assessing local tumor invasiveness remains poorly understood.
Humans Prognosis Female Aged Adult Breast Neoplasms Biomarkers, Tumor Middle Aged Lymphatic Metastasis Iran Neovascularization, Pathologic Receptor, ErbB-2 Receptors, Estrogen Receptors, Progesterone Vascular Endothelial Growth Factor C Lymphangiogenesis Receptor, TIE-2 Angiopoietin-2 Angiopoietin-1
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