AI Medical Compendium

σ-p Hyperconjugation-Enabled Covalent Organic Frameworks for Programmable Cascaded Optical Modulation.

Advanced materials (Deerfield Beach, Fla.) May 31, 2026

σ-p hyperconjugation is identified as an effective molecular lever for regulating the excited-state behavior and donor characteristics of covalent organic frameworks (COFs). Activation of σ-p hyperconjugation amplifies the fluorescence quantum yield ... read more

Molecular Engineering of the Nano-Bio Interface for Programmable and Precision Protein Delivery.

Advanced materials (Deerfield Beach, Fla.) May 31, 2026

Protein therapeutics offer unparalleled specificity and immediate bioactivity for addressing complex pathologies; however, their vast therapeutic potential is fundamentally constrained by intrinsic structural vulnerability and the formidable barrier ... read more

Deep Learning Assisted Motion Behavior Analysis of Catalytic Micromotors Based on Trajectory and Optical Flow.

Nano letters May 31, 2026

Investigating micro/nanomotors' (MNMs') motion behavior is crucial for their practical applications and fundamental understanding of propulsion mechanisms. However, existing methods focus exclusively on a single-drive system and lack discriminative c... read more

Mechanistic Insights into PET-MPs-Aggravated Ischemic Stroke via Integrated Computational-Experimental Approaches.

Environmental science & technology May 31, 2026

Microplastics, especially the environmentally pervasive polyethylene terephthalate microplastics (PET-MPs), are important environmental pollutants, and their potential risks to the health of the nervous system are increasingly a concern. Evidence ind... read more

Integrated Network Pharmacology, Molecular Docking, and Experimental Validation for Uncovering the Pharmacodynamic Basis of Sanghuang against Human Pulmonary Fibrosis.

Combinatorial chemistry & high throughput screening May 31, 2026

INTRODUCTION/OBJECTIVE: Sanghuang, a traditional Chinese medicinal fungus, exhibits well-documented anti-inflammatory, antioxidant, and antitumor activities. Emerging preclinical evidence indicates its efficacy in ameliorating bleomycin-induced Pulmo... read more

Morpho-functional plasticity of tumour-associated macrophages: linking cell shape, ultrastructure, and immune regulation in cancer.

Clinical and experimental medicine May 31, 2026

Macrophages are highly adaptable immune cells that play dual roles in the tumor microenvironment (TME), either promoting or restraining tumor progression. Their polarization into M1 and M2 tumor-associated macrophage (TAM) phenotypes is classically d... read more

An AI-Driven Pipeline for Localization, Segmentation, and Classification of Carpal Tunnel Syndrome Using Ultrasound Images of the Median Nerve.

Hand (New York, N.Y.) May 30, 2026

BACKGROUND: Carpal tunnel syndrome (CTS), the most common peripheral neuropathy, is currently diagnosed by clinical suspicion supported by tools such as the CTS-6 questionnaire and ultrasound. While these tools are widely used and clinically valuable... read more

Prediction of low birth weight using machine learning-based analysis of environmental and maternal risk factors: insights from the Korean CHildren's ENvironmental health Study (Ko-CHENS).

Environmental research May 30, 2026

Adverse birth outcomes such as low birth weight (LBW) increase the risk of metabolic disorders and hypertension later in life. Although previous studies have examined obstetric factors or environmental exposures in relation to LBW, few have assessed ... read more

Guideline Adherence in the Diagnosis of PCOS Among Adolescents: Comparing Obstetricians and Gynecologists With Large Language Models.

Journal of pediatric and adolescent gynecology May 30, 2026

STUDY OBJECTIVE: Polycystic ovary syndrome in adolescence is a condition associated with long-term cardiovascular, metabolic, and psychological outcomes. The diagnosis of PCOS in adolescence poses diagnostic challenges for obstetricians and gynecolog... read more

Identification and multicenter validation of a 4-gene plasma signature for early recognition and risk assessment in hypertensive intracerebral hemorrhage.

Genomics May 30, 2026

Hypertensive intracerebral hemorrhage (ICH) is a devastating stroke subtype with high mortality and disability, yet reliable early risk biomarkers remain elusive. This study integrated protein microarray and transcriptomics with machine learning to i... read more

Artificial Intelligence Medical Compendium